Efficacy and safety of tap water iontophoresis for palmoplantar hyperhidrosis
Keywords:
Tap water iontophoresis, hyperhidrosisAbstract
Objective To evaluate the efficacy and safety of tap water iontophoresis (TWI) for the treatment of palmoplantar hyperhidrosis in our local setting. Patients and methods Thirteen patients of idiopathic palmoplantar hyperhidrosis were enrolled in the study from the Department of Dermatology, Lahore Medical and Dental College/Ghurki Hospital and Skin Clinic, Gulberg, Lahore from May 2009 to August 2012. Two patients dropped out, and the study was completed by eleven patients. The patients were treated with TWI three times a week for six weeks and followed up at twelve weeks. Each session lasted for 20 minutes, with the polarity being reversed after 10 minutes. The results were assessed by the hyperhidrosis disease severity index, improvement of sweating on a scale of I to IV and the starch-iodine test. Any adverse events were noted. Results All the patients responded well to the treatment with minimal discomfort. Conclusion Tap water iontophoresis is a safe, effective, inexpensive and affordable treatment modality for palmoplantar hyperhidrosis. It improves quality of life significantly during treatment.ÂReferences
Hornberger J, Grimes K, Neuman M et al. Recognition, diagnosis and treatment of primary focal hyperhidrosis. J Am Acad Dermatol. 2004;51:274-86.
Swartling C, Naver H, Lindberg M. Botulinum A toxin improves life quality in severe primary focal hyperhidrosis. Eur J Neurol. 2001;8:247-52.
Naumann MK, Hamm H, Spalding JR et al. Comparing the quality of life effect of primary focal hyperhidrosis as assessed by the Dermatology Life Quality Index (DLQI). Paper presented at the July 2003 meeting of the American Academy of Dermatology; July 25–29, 2003; Chicago, Ill.
Sato K, Kang WH, Saga K, Sato KT. Biology of sweat glands and their disorders. II. Disorders of sweat gland function. J Am Acad Dermatol. 1989;20:713-26.
Manusov EG, Nadeau MT. Hyperhidrosis: a management dilemma. J Fam Pract. 1989;28:412-5.
Stolman LP. Treatment of excess sweating of the palms by iontophoresis. Arch Dermatol. 1987;123:893-6.
Dahl JC, Gland Madsen L. Treatment of hyperhidrosis manuum by tap water iontophoresis. Acta Derm Venereol Stockh. 1989;69:346-8.
Shelley WB, Talanin NY, Shelley ED. Botulinum toxin therapy for palmar hyperhidrosis. J Am Acad Dermatol. 1998;38:227-9.
Moran KT, Brady MP. Surgical management of primary hyperhidrosis. Br J Surg. 1991;8:279-83.
Bonjer HJ, Hamming JF, DuBois NAJJ et al. Advantages of limited thoracoscopic sympathectomy. Surg Endosc. 1996;10:721-3.
To ̈gel B, Greve B, Raulin C. Current therapeutic strategies for hyperhidrosis: a review. Eur J Dermatol. 2002;12:219-23.
Bouman HD, Lentzer EM. The treatment of hyperhidrosis of the hands and feet with constant current. Am J Phys Med. 1952;31:158-69.
Levit F. Simple device for the treatment of hyperhidrosis by iontophoresis. Arch Dermatol. 1968;98:505-7.
Shen JL, Lin GS, Li WM. A new strategy of iontophoresis for hyperhidrosis. J Am Acad Dermatol. 1990;22 (2 Part 1):239-41.
Chan LY, Tang WYM, Lo KK et al. Treatment of palmar hyperhidrosis using tap water iontophoresis: local experience. HKMJ. 1999;5;191-4.
Templeton EA, Sato E, Sato K. Mechanism of action of tap water iontophoresis for hyperhidrosis and simple innovation for improving its efficacy. J Invest Dermatol. 1985;84:360.
Shelley WB, Horvath PN, Weidman F et al. Experimental miliaria in man: production of sweat retention, anhidrosis, and vesicles by means of iontophoresis. J Invest Dermatol. 1948;11:275-89.
Holzle E, Ruzicka T. Treatment of hyperhidrosis by a battery-operated iontophoretic device. Dermatologica. 1986;172:41-7.
Stratton DR, Kowalski JW, Galser DA, Stang PE. US prevalence of hyperhidrosis and impact on individuals with axillary hyperhidrosis: results from a national survey. J Am Acad of Dermatol. 2004;51:241-8.
