Association between streptococcal throat infection and psoriasis in Bangladesh
DOI:
https://doi.org/10.66344/jpad.23.4.2013.285Keywords:
Streptococcal infection, association, psoriasisAbstract
Objective To assess the association between streptococcal throat infection and psoriasis. Patients and methods Total one hundred fourteen (114) patients attending at outpatient and inpatient department of Dermatology and Venereology, Bangabandhu Sheikh Mujib Medical University, Dhaka were selected for our study. Patients clinically and histopathologically diagnosed as psoriasis were selected as case group and patients with skin diseases other than psoriasis were selected as control group. Results In our study, mean age was 30.73±14.69 years in cases and 26.47±12.64 years in controls. Majority of respondents were diagnosed as chronic plaque psoriasis (51%) among acute guttate psoriasis, guttate flare of chronic plaque psoriasis, deterioration of chronic plaque psoriasis and pustular psoriasis. 19 (30%) patients of psoriasis had sore throat clinically. ASO titer was raised in 65% psoriatics and 19.6% non-psoriatic controls. Majority of cases of guttate psoriasis (86.6%) had raised ASO titer versus 27.2% respective controls. Normal flora was the maximum finding in two groups and Streptococcus pyogenes was the second highest in frequency in both sides. In throat swab culture results of two groups, 15 (23.8%) psoriasis patients and 5 (9.8%) non-psoriatic controls were found positive for S pyogenes.  Conclusion Streptococcal throat infection can cause provocation of psoriasis. So, psoriasis patients should be encouraged to report sore throat to their physician and early treatment of streptococcal throat infections might be beneficial in psoriasis.ÂReferences
Neimann AL, Porter SB, Gelfand JM. The epidemiology of psoriasis. Expert Rev Dermatol. 2006;1:63-75.
Sabat R, Philipp S, Hoflich C et al. Immunopathogenesis of psoriasis. Exp Dermatol. 2007;16:779-98.
Terui T, Ozawa M, Tagami H. Role of neutrophils in induction of acute , inflammation in T-cell-mediated immune dermatosis, psoriasis: A neutrophil-associated inflammation-boosting loop. Exp Dermatol. 2000;9:1-10.
Gudjonsson JE, Thorarisson AM, Sigurgeirsson B et al. Streptococcal throat infections and exacerbation of chronic plaque psoriasis: a prospective study. Br J Dermatol. 2003;149:530-4.
Toichi E, Tachibana T, Furukawa F. Rapid improvement of psoriasis vulgaris during drug-induced agranulocytosis’. J Am Acad Dermatol. 2000;43:391-5.
Weisenseel P, Laumbacher B, Besgen P. Streptococcal infection distinguishes different types of psoriasis. J Med Genet. 2002;39:767-8.
McFadden J, Valdimarsson H, Fry L. Cross-reactivity between streptococcal M surface antigen and human skin. Br J Dermatol. 1991;125:443-7.
Telfer NR, Chalmers RJG, Whale K, Colman G. The role of streptococcal infection in the initiation of guttate psoriasis. Arch Dermatol. 1992;128:39-42.
Darrow DH, Buescher ES. Group A streptococcal pharyngitis. Curr Opin Otolaryngol Head Neck Surg. 2002;10:449-54.
Chaudhary S, Bilinsky SA, Hennessy JL. Penicillin V and rifampin for the treatment of group A streptococcal pharyngitis: a randomized trial of 10 days penicillin vs 10 days penicillin with rifampin during the final 4 days of therapy. J Pediatr.1985;106:481-6.
Naldi L, Griffiths CEM. Traditional therapies in the management of moderate to severe chronic plaque psoriasis: an assessment of the benefits and risks. Br J Dermatol. 2005;152:597-615.
Naqqash S, Uddeen Tameez, Naqqash SH, Butt AK. Family history of psoriasis and recent infectious disease are risk factor for the first episode of acute guttate psoriasis. J Pak Assoc Dermatol. 2004;14:124-9.
Mukherjee SK. Streptococcal infection as trigger for psoriasis. Contempor Pediatr. 2011;2:207-15.
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