To compare the efficacy of 35% glycolic acid along with micro-needling versus platelet rich plasma along with micro-needling in treatment of the acne scars
Keywords:
Acne vulgaris, ; Micro-needling, Platelet rich plasma, glycolic acid (GA), Post-acne atrophic scarsAbstract
OBJECTIVE: To compare the efficacy of 35% glycolic acid combined with micro-needling versus platelet rich plasma combined with micro-needling in the treatment of acne scars METHODOLOGY: This randomized controlled study was conducted at Department of Dermatology, Mayo Hospital, Lahore from July 16, 2022 to January 15, 2023. 60 patients fulfilling the selection criteria were enrolled. Group A went through micro-needling combined with 35% glycolic acid (containing glycolic acid) and group B went through micro-needling combined with platelet rich plasma. Scars were examined before the first treatment session and at each follow up and scored according to Goodman and Baron’s Qualitative Acne Scarring Grading System. Final visit was done after 4 weeks of last session. Both groups were compared for efficacy using Chi-square test taking p-value ≤0.05 as significant. RESULTS: In group-A, 7(23.3%) were males and 23(76.7%) were females, while in group-B, 8(26.7%) were males and 22(73.3%) were females. The mean age of patients in group-A was 23.68±5.03 years and 24.48±4.75 years in group-B. In Micro-needling plus 35% glycolic acid group, 26(86.7%) patients had efficacy of treatment, while in Micro-needling plus PRP group, 19(63.3%) patients had efficacy of treatment (p<0.05). CONCLUSION: Micro-needling combined with 35% glycolic acid is a more effective therapeutic modality than micro-needling combined with PRP. KEY WORDS: Acne Vulgaris, Micro-Needling, Platelet Rich Plasma, 35% Glycolic Acid, Post-Acne Atrophic Scars.References
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