Frequency of HIV seropositivity in patients with sexually transmitted infections presenting in the dermatology department of a tertiary care hospital

Authors

  • Burhan Ashraf
  • Shehla Shaukat KEMU/ Mayo Hospital Lahore
  • Mahwish Zahoor
  • Tahir Jamil Ahmad
  • Ijaz Hussain

Keywords:

Sexually transmitted infections, HIV, ELISA

Abstract

Introduction As the Human Immunodeficiency virus/ Acquired Immunodeficiency Syndrome (HIV/AIDS) continue to advance worldwide, sexually transmitted infections (STIs) rates remain high in much of the world. Each year about 330 million new cases of STIs occur, of which more than 90% are in developing countries. Prevalence of HIV in people effected with STIs is 10 times more as compared to general population i.e. 10%. Objectives To determine the frequency of HIV in patients who are presenting for the treatment of STIs in dermatology department of tertiary care hospital. Methods A descriptive cross-sectional study was conducted in the Department of Dermatology, KEMU/Mayo Hospital, Lahore in collaboration with Punjab AIDS Control Program (PACP). Study was carried out over a period of six months from 20-12-2016 to 19-06-2017. A total of 285 patients were included in the study. Whole blood sample was taken and tested for HIV using kit provided by PACP. Patients were also evaluated and investigated for the type of their STI and medications given for treatment of their STIs. HIV was confirmed by ELISA and they were referred to HIV clinic Mayo hospital, Lahore for further management. Results Mean age of the patients was 30 years. There were 153 males (53.7%), 121 females (42.5%) while 11 patients (3.8%) were hijras. Married patients were 55% and 45% patients were unmarried. Sexual orientation vise there were 8.8% homosexuals, 87.7% heterosexuals and 3.5% bisexuals. Out of 285 patients, 34% used condoms. History of blood transfusion was found in 4%. History of IV drug abuse was given by 5%. Types of STIs were as follows: warts 36%, secondary syphilis 20%), scabies 20%, tinea cruris 9%, vaginal discharge 11%), gonorrhoea 2%), and genital herpes 3%). Majority of the patients (88%) had 1-4 sexual partners. HIV positive patients found among these patients with STIs were 24 (8%). Conclusion In conclusion, the frequency of HIV among patients with STIs was 8%. To prevent HIV/STIs, campaigns promoting condom use are needed to boost the frequency of condom use. 

Author Biography

Shehla Shaukat, KEMU/ Mayo Hospital Lahore

Assistant professor, dermatology unit -1, KEMU/mayo hospital, lahore

References

Andrew MQ, Michael JA, Elliot JL, Eric BC, editors. Virus Taxonomy: Ninth Report of the International Committee on Taxonomy of Viruses. 9th ed. London: Elsevier; 2011.

Weiss RA. How does HIV cause AIDS? Science 360.1993;260:1273-9.

Pence GE. Preventing the Global Spread of AIDS. In Medical Ethics Accounts of the Cases That Shaped and Define Medical Ethics. New York: McGraw-Hill; 2008. p. 330.

Dolin, Gerald LM, John EB. Mandell, Douglas and Bennett's principles and practice of infectious diseases. 7th ed. Philadelphia, PA: Churchill Livingstone/Elsevier; 2010. p. 2323-27.

Global HIV & AIDS statistics — 2019 fact sheet. Available at:

https://www.unaids.org/en/resources/fact-sheet

Yousaf MZ, Zia S, Babar ME, Ashfaq UA. The epidemic of HIV/AIDS in developing countries; the current scenario in Pakistan. Virol J 2011;8:401.

Pakistan National AIDS Control Program. Available at: http://www.nacp.gov.pk/index.html Date accessed: June 8, 2019

Ahmed A. Hashmi FK, Khan GM. HIV outbreaks in Pakistan. Lancet. 2019;6(7):418.

llyas M, Asad S, All L, Shah M, Badar S, Sarwar MT, et al. A situational analysis of HIV and AIDS in Pakistan. Virol J 2011;8:191.

Report on global sexually transmitted infection surveillance, 2018. Geneva: World Health Organization; 2018. Licence: CC BY-NC-SA 3.0 IGO.

World Health Organization. Sexually transmitted infections (STIs) Fact sheet No 110. 2013 Nov [Online] [Cited 2015 Dec]. Available from: http://www.who.int/mediacentre/factsheets/fs110/en/

Shaukat S, Kazmi AH. Sexually transmitted infections and syndromic management. J Pak Assoc Dermtol 2015;25:159-61.

Khan AA, Khan A. Sexually transmitted infection care in Pakistan: The providers perspective. J Pak Med Assoc 2012;62:941.

National AIDS Control Program, Ministry of Health Pakistan. The STI Prevalence Study of Pakistan. 2001 [Online] [Cited 2015 August 10]. Available from: http://www.nacp.gov.pk/library/reports/ summary-sti-prevalence-study-in-pakistan-2000.pdf html

World Health Organization. Global Prevalence and Incidence of Selected Curable Sexually Transmitted Infections: Overview and Estimates. [Cited 2015 August 18]. Available from: http://www.who.int/hiv/pub/sti/who_hiv_aids_2001.02.pdf .html.

Khan AA, Rehan N, Qayyum K, Khan A. Care seeking for STI symptoms in Pakistan. J Pak Med Assoc 2009;628:59.

Hayes R, Jones DW. Celum C. Wijgert J, Wasserheit J. Treatment of sexually transmitted infections for HIV prevention: end of the road or new beginning?. AIDS 2010;24:S 15-26.

Peterman TA, Newman DR, Maddox L, Schmitt K, Shiver S. Extremely High Risk for HIV following a diagnosis of syphilis among men living in Florida, 2000-2011. Pub Health Rep 2014;129:164-9.

Bhurgri Y. HIV/AIDS in Pakistan. J Pak Med Assoc. 2006;1:553.

Wasserheit J. Epidemiological synergy. Interrelationships between human immunodeficiency virus infection and other sexually transmitted diseases. Sex Transm Dis 1992:61–77.

Rogers A, Meundi A, Amma A. HIV-related knowledge, attitudes, perceived benefits, and risks of HIV testing among pregnant women in rural southern India. AIDS Patient Care STDs 2006;20: 803–11.

White R, Orroth KK, Korenromp EL. Can population differences explain the contrasting results of the Mwanza, Rakai, and Masaka HIV/Sexually Transmitted Disease Intervention Trials? J Acquir Immune Defic Syndr 2004;37:1500–13.

Korenromp E, White RG, Orroth KK. Determinants of the impact of sexually transmitted infection treatment on prevention of HIV infection: A synthesis of evidence from the Mwanza, Rakai, and Masaka Intervention Trials. J Infect Dis 2005;191: S168–178.

Amin SS, Urfi, Sachdeva S, Kirmani S, Kaushal M. Clinico-social profile of sexually transmitted infections and HIV at a tertiary care teaching hospital in India. Community Acquir Infect. 2014;1:25–8.

Shendre MC, Tiwari RR. Social risk factors for sexually transmitted diseases. Indian J Dermatol Venereol Leprol 2001;68:25-7.

Kumar B, Handa S, Malhotra S. Changing trends in sexually transmitted diseases. Indian J Sex Transm Dis 1995;16:24-7.

Nair TV, Asha LK, Leelakumari PV. An epidemiological study of sexually transmitted diseases. Indian J Dermatol Venereol Leprol 2000;66:69-72.

Choudhry S, Ramachandran VG, Das S, Bhattacharya SN, Mogha NS. Characterization of patients with multiple sexually transmitted infections: A hospital-based survey. Indian J Sex Transm Dis 2010;31:87-91

Narayan B. A retrospective study of the pattern of sexually transmitted diseases during a ten-year period. Indian J Dermatol Venereol Leprol 2005;71:333-7.

Madhivanan P, Hernandez A, Gogate A. Alcohol use by men is a risk factor for the acquisition of sexually transmitted infections and human immunodeficiency virus from female sex workers in Mumbai, India. Sex Transm Dis 2005;32:685–90.

Setia M, Lindan C. Men who have sex with men and transgenders in Mumbai, India: An emerging risk group for STIs and HIV. Indian J Dermatol Venereol Leprosy 2006;72:425–31.

Divekar A. Gogate AS. Shivkar LK. Gogate S. Badhwar VR. Disease prevalence in women attending the STD clinic in Mumbai (formerly Bombay), India. Int J STD AIDS 2000;11:45–8.

Panda S, Kumar MS, Saravanamurthy PS. Sexually transmitted infections and sexual practices in injection drug users and their regular sex partners in Chennai, India. Sex Transm Dis 2007;34:250–3.

Devi SA, Vetrichevvel TP, Pise GA, Thappa DM. Pattern of sexually transmitted infections in a tertiary care centre at Puducherry. Indian J Dermatol 2009;54:347-9.

Carpenter L, Kamali A. Independent effects of reported sexually transmitted infections and sexual behavior on HIV-1 prevalence among adult women, men, and teenagers in rural Uganda. J Acquir Immune Defic Syndr 2002;29:174–80.

Sabin K, Rahman M, Hawkes S, Ahsan K, Begum L, Black RE, et al. Sexually transmitted infections prevalence rates in slum communities of Dhaka, Bangladesh. Int J STD AIDS 2003;14:614–21.

Sarkar S, Shrimal A, Das J, Choudhury S. Pattern of sexually transmitted infections: A profile from a sexually transmitted infections clinic of a tertiary care hospital of Eastern India. Ann Med Health Sci Res 2013;3:206-9.

Vora R, Anjaneyan G, Doctor C, Gupta R. Clinico-epidemiological study of sexually transmitted infections in males at a rural-based tertiary care center. Indian J Sex Transm Dis 2011;32:86-9.

White R, Orroth KK, Korenromp EL. Can population differences explain the contrasting results of the Mwanza, Rakai, and Masaka HIV/Sexually Transmitted Disease Intervention Trials? J Acquir Immune Defic Syndr 2004;37:1500–13

Downloads

Published

2020-09-30

Issue

Section

Original Articles

Most read articles by the same author(s)

1 2 3 4 5 6 7 8 9 10 > >>