Epidermodysplasia verruciformis: a rare genodermatosis with risk of malignant transformation
DOI:
https://doi.org/10.66344/jpad.16.4.2006.891Keywords:
Epidermodysplasia verruciformis, human papillomavirus, verruca planaAbstract
Epidermodysplasia verruciformis is a rare, lifelong, autosomal recessive hereditary disorder affecting the skin and is characterized by chronic infection with human papillomavirus. We report a case of young boy who presented with widespread pityriasis versicolor-like lesions and was mistreated as fungal infection for some time. A brief review of the condition is also given below. ÂReferences
Joblonska S. Epidermodysplasia verruciformis. In: Friedman RJ, ed. Skin Cancers. Philadelphia: WB Saunders; 1991. p. 101-13.
Lutzner MA, Blanchet-Bardon C, Orth G. Clinical observations, virologic studies, and treatment trials in patients with epidermodysplasia verruciformis, a disease induced by specific human papillomaviruses. J Invest Dermatol 1984; 83: 18s-25s.
Oliveira WRP, Carrasco S, Festa C et al. Nonspecific cell-mediated immunity in patients with epidermodysplasia verruciformis. J Dermatol 2003; 30: 203-9.
Purdie KJ, Surentheran T, Sterling JC et al. Human papillomavirus gene expression in cutaneous squamous cell carcinomas from immunosuppressed and immunocompetent individuals. J Invest Dermatol. 2005; 125: 98-107.
Majewski S, Jablonska S. Epidermodysplasia verruciformis as a model of human papillomavirus-induced genetic cancer of the skin. Arch Dermatol 1995; 131: 1312-8
Micali G, Nasca MR, Dall'Oglio F, Musumeci ML. Cimetidine therapy for epidermodisplasia verruciformis. J Am Acad Dematol 2003; 48: S9-S10.
Anadolu R, Oskay T, Erdem C, Boyvat A et al. Treatment of epidermodysplasia verruciformis with a combination of acitretin and interferon alfa-2a. J Am Acad Dermatol 2001; 45: 296-9.
Oliveira WR, Festa C, Rady P, Tyring SK. Seborrheic keratosis-like lesions in patients with epidermodysplasia verruciformis. J Dermatol 2003; 30: 48-53.
Downloads
Published
How to Cite
Issue
Section
License
Submission declaration
Authors retain the copyright to their work and grant the 'Journal of Pakistan Association of Dermatologists (JPAD)' the right of first publication under a Creative Commons Attribution 4.0 International (CC BY 4.0) license. This license allows others to share, adapt, and reuse the work for any purpose, including commercial use, as long as appropriate credit is given to the original authors and the journal.
By submitting a manuscript, authors confirm that the work has not been published previously (except as an abstract, lecture, or academic thesis), is not under review elsewhere, and has been approved by all authors and relevant authorities. Once accepted, the article will be openly accessible under the CC BY 4.0 license, ensuring wide dissemination and reuse with proper attribution.
