Disseminated Orf: An uncommon presentation

Authors

  • Maleeha Jawaid Bahria University Medical And Dental College
  • Muhammad Irfan Anwar Bahria University Medical And Dental College
  • Arfan Ul Bari Bahria University Medical And Dental College

DOI:

https://doi.org/10.66344/jpad.v30i4.1505

Keywords:

Orf, Poxvirus, Ecthyma contagiosum

Abstract

Orf or Ecthyma contagiosum is a viral dermatosis found mainly in animals, and in humans via zoonotic transmission from an infected animal. We herein, describe a case of Orf in an immunocompetent lady with a positive history of direct contact with a diseased animal in her neighbourhood. The patient presented to us in the out-patient department with multiple, large, ulcerated violaceous nodules on both her upper and lower limbs. The diagnosis was made on clinical grounds. It was later confirmed via histopathology. Where we might regard orf as a solitary appearing nodule, its unusual clinical patterns must not be missed in order to avoid unnecessary investigations and interventions.

Author Biographies

  • Maleeha Jawaid, Bahria University Medical And Dental College
    Resgistrar Dermatology
  • Muhammad Irfan Anwar, Bahria University Medical And Dental College
    Working as Asst Prof Of dermatology
  • Arfan Ul Bari, Bahria University Medical And Dental College
    Asst Prof Of dermatology

References

1. Groves RW, Wilson-Jones E, MacDonald DM. Human orf and milkers' nodule: A clinicopathologic study. J Am Acad Dermatol. 1991;25(4):706-11.

2. Bergqvist C, Kurban M, Abbas O. Orf virus infection. Rev Med Virol. 2017;27(4):e1932.

3. Spyrou V, Valiakos G. Orf virus infection in sheep or goats. Vet Microbiol. 2015; 181(1):178-82.

4. Espósito ACC, Jorge MFS, Marques MEA, Abbade LPF. Milker's nodules: classic histological findings. Anais brasileiros de dermatologia.2017;92(6):838-40.

5. Biazar T, Shokri M, Hosseinnia H, Bayani M. Erythema Multiforme as a Result of Orf Disease; a Case Report. Emergency (Tehran, Iran). 2016;4(3):163-5.

6. Zhao K, He W, Gao W, Lu H, Han T, Li J, et al. Orf virus DNA vaccines expressing ORFV 011 and ORFV 059 chimeric protein enhances immunogenicity. Virol J. 2011; 8:562.

7. Higgins E, Bennett M, Murphy A, Markham T. Disseminated parapox (orf) in a 13-year-old boy with atopic dermatitis following acupuncture. Clin Exp Dermatol. 2011; 36(7):809-11.

8. Sasmaz S, Uzel M, Sener S, Ucmak H. Rare presentation of human orf as multiple lesions. J Dermatol. 2011;38(8):825-6.

9. Hsu CH, Rokni GR, Aghazadeh N, Brinster N, Li Y, Muehlenbachs A, et al. Unique Presentation of Orf Virus Infection in a Thermal-Burn Patient After Receiving an Autologous Skin Graft. J Infec Dis. 2016;214(8):1171-4.

10. Afia Z, Robert S, Roger H, Mazhar N, Altaf A, Akhtar H, et al. Nosocomial Buffalopoxvirus Infection, Karachi, Pakistan. Emerg Infecti Dis. 2007;13(6):902.

Downloads

Published

04.01.2021

How to Cite

1.
Disseminated Orf: An uncommon presentation. J Pak Assoc Dermatol [Internet]. 2021 Jan. 4 [cited 2026 Jul. 19];30(4):682-5. Available from: https://www.jpad.com.pk/index.php/jpad/article/view/1505