Sclerotherapy as a non-surgical treatment for eccrine angiomatous hamartoma in children: A case series

Abstract

Background Eccrine angiomatous hamartoma (EAH) is a rare comprising benign skin lesions eccrine glands and vascular channels, usually causing pain and localized sweating in children. Surgical excision, the standard treatment, can cause scarring and is not often feasible for lesions near joints.   Objective To assess sclerotherapy as a non-surgical treatment for eccrine angiomatous hamartoma in children. Methods Four children (age range 2.5-13 years; three boys, one girl) with biopsy-confirmed EAH involving the lower limbs have been treated with weekly intralesional injections of 3% polidocanol. Lesion sizes ranged from 2 × 3 cm to 7 × 7 cm. Treatment was continued until clinical improvement, with sessions ranging from 8 to 12 per patient. Follow-up ranged from 2 to 3 months. Results All four patients exhibited reduction in lesion size, ranging from approximately 50 to 80%. Pain terminated completely in three patients and improved substantially in one. One patient with localized hyperhidrosis recorded decreased sweating. During injection, patients encounter brief stinging that subsided within minutes. No ulceration or necrosis happened. Conclusion Intralesional 3% polidocanol showed good tolerance to the treatment, with few minimal and self-limiting symptoms which did not require additional intervention option for EAH in children, with short-term improvement in size and symptoms. Longer follow-up is required to assess durability and recurrence.