Childhood-onset systemic lupus erythematosus – A case report

Authors

  • Amit Kumar Department of Dermatology, Venereology & Leprosy, RIMS, Bariatu, Ranchi
  • Pradeep Kumar Department of Dermatology, Venereology & Leprosy, RIMS, Bariatu, Ranchi
  • Masuma P Bhengra Department of Dermatology, Venereology & Leprosy, RIMS, Bariatu, Ranchi
  • Prabhat Kumar Department of Dermatology, Venereology & Leprosy, RIMS, Bariatu, Ranchi
  • Syam Sundar Chaudhary Department of Dermatology, Venereology & Leprosy, RIMS, Bariatu, Ranchi

DOI:

https://doi.org/10.66344/jpad.v26i1.80

Keywords:

Systemic lupus erythematosus, childhood-onset SLE

Abstract

Systemic lupus erythematosus (SLE) is autoimmune multisystem disease associated with various clinical manifestations. Childhood-onset SLE (cSLE) is extremely rare and comprises only 15-20% of lupus erythematosus cases. Most of the children belong to the adolescent group while very few are in the prepubertal age. We herein, report a case of 7-year-old female child diagnosed as systemic lupus erythematosus due to its rare occurrence in  pediatric age group.

References

1. Cassidy JT. SLE, Juvenile dermatomyositis, Scleroderma, and Vasculitis. In: Kelly WN, Harris ED, Ruddy S, Sledge CB, editors. Textbook of Rheumatology, 4th edn. Philadelphia, WB Saunders; 1993. P. 1224-47.

2. Ali VS, Dalvi AS, Merchant RH, Mehta KP, Chadlani AT, Badakere SS et al. Systemic lupus erythematosus in Indian children. Indian J Pediatr. 1989;26:868-73.

3. Chandrashekharan AN, Rajendra CP, Ramakrishnan S, Madhavan R, Pratibhan M. Childhood systemic lupus erythematosus in south India. Indian J Pediatr. 1994;61:223-9.

4. Lehman TJ, McCurdy D, Spencer C. Prognostic value of antibodies to Ro/SSA, SSB/La, and RNP in children with systemic lupus erythematosus (abstract). Arthritis Rheum. 1990;33(Suppl):S154.

5. Segel M, Lee SL. The epidemiology of systemic lupus erythematosus. Semin Arthritis Rheum. 1973;3:154.

6. Tucker LB, Menon S, Schaller JG, Isenberg DA. Adult- and childhood-onset systemic lupus erythematosus: a comparison of onset, clinical features, serology, and outcome. Br J Rheumatol. 1994;34:866-72.

7. Jimenez S, Cervera R, Font J, Ingelmo M. The epidemiology of systemic lupus erythematosus. Clin Rev Allergy Immunol. 2003;25:3-12.

8. Von Feldt JM. Systemic lupus erythematosus. Recognizing its various presentations. Postgrad Med. 1995;97: 79, 83, 86.

9. Pande J, Sekharan NG, Kailash S, Uppal SS, Singh RR, Kumar A et al. Analysis of clinical and laboratory profile in Indian childhood systemic lupus erythematosus and its comparison with SLE in adults. Lupus. 1993;2:83-7.

10. Tucker LB, Menon S, Schaller JG, Isenberg DA. Adult- and childhood-onset systemic lupus erythematosus. A comparison of onset, clinical features, serology and outcome. Br J Rheumatol. 1995;34:866-72.

11. Janwityanujit S, Totemchokchyakarn K, Verasertniyom O, Vanichapuntu M, Vatanasuk M. Age related differences on clinical and immunological manifestations of SLE. Asian Pac J Allergy Immunol. 1995;13:145-9.

12. Font J, Cervera R, Espinosa G, Pallarés L, Ramos-Casals M, Jiménez S et al. Systemic lupus erythematosus (SLE) in childhood: analysis of clinical and immunological in 35 patients and comparison with SLE characteristics in adults. Ann Rheum Dis. 1998;57:456-9.

13. Livingston B, Bonner A, Pope J. Differences in clinical manifestations between childhood-onset lupus and adult-onset lupus: a meta-analysis. Lupus. 2011;15:1345-55. doi: 10.1177/0961203311416694.

14. Quintero-Del-Rio Al, Van Miller. Neurologic symptoms in children with systemic lupus erythematosus. J Child Neurol. 2000;15:803-7.

15. Carreno L, Lopez-Longo FJ, Monteagudo I et al. Immunological and clinical differences between juvenile and adult onset systemic lupus erythematosus. Lupus. 1999;8:287-92.

Downloads

Published

18.11.2016

Issue

Section

Case Reports

How to Cite

1.
Childhood-onset systemic lupus erythematosus – A case report. J Pak Assoc Dermatol [Internet]. 2016 Nov. 18 [cited 2026 Jul. 22];26(1):76-9. Available from: https://www.jpad.com.pk/index.php/jpad/article/view/80