Acrodermatitis enteropathica in three siblings
Abstract
Acrodermatitis enteropathica is an autosomal recessive disease due to a partial disorder of intestinal zinc uptake. Signs usually appear within the first months of life, with a characteristic cutaneous rash that is symmetrical, located around the body orifices, behind the ears, and on hands, feet, and head. We report three siblings with characteristic features of the disease and laboratory evidence of low serum zinc levels. Symptoms in all three patients reversed remarkably on supplementation of zinc. A brief history, clinical profile, pathophysiology and treatment of the disease have also been discussed in this article for better understanding of this disorder.References
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