Comparative evaluation of hydroquinone, tretinoin and mometasone versus glycolic acid versus trichloroacetic acid peel in melasma
DOI:
https://doi.org/10.66344/jpad.v26i1.71Keywords:
Melasma, hydroquinone, tretinoin, mometasone, glycolic acid, trichloroacetic acidAbstract
Objective Comparative evaluation of 2% hydroquinone, 0.025% tretinoin and 1% mometasone versus glycolic acid and trichloroacetic acid peel alone in melasma.
Methods Seventy five patients were included in the study. Total duration of study was one and a half years. Melasma area severity index (MASI) score of more than 10 were included in the study. The patients were divided into three groups. Group A consisted of 25 patients and were given 2% Hydroquinone, mometasone 1% and 0.025% tretinoin. Group B consisted of 25 patients and underwent glycolic acid peel. Group C consisted of 25 patients and underwent trichloroacetic acid peel.
Results Group A had better response, followed by group B and group C, respectively.
Conclusion Combination of hydroquinone, mometasone and tretinoin is a good option to treat melasma only when used judiciously along with sunscreen, whereas glycolic acid peels are a safer option with fewer side effects.
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Copyright (c) 2016 Seeba Hussain, Md Raihan, Abhijeet Kumar Jha, Satyaki Ganguly, Kranti Chandan Jaykar, Paritosh Kumar Banerjee
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