Mucocutaneous leishmaniasis: does it really exist in Pakistan?
Keywords:
Mucocutaneous leishmaniasis, cutaneous leishmaniasis, Leishmania parasite, LT (Leishmaina trophozoite) bodies.Abstract
Mucocutaneous leishmaniasis is considered to be a disease of the New World. It has rarelybeen reported from our part of the world. A 2-year-old child reported from an endemic areaof cutaneous leishmaniasis with clinically suggestive lesions of CL over cutaneous as well asmucosal surfaces of the lip and nose. Diagnosis was confirmed on slit skin smear preparationand he was treated with intramuscular injection of meglumine antimonite (glucantime). Abrief review of the condition is also presented along with the case report.References
Herwaldt BL. Leishmaniasis. Lancet
; 354: 1191-9.
David C, Dimier-David L, Vargas F et
al. Fifteen years of cutaneous and
mucocutaneous leishmaniasis in
Bolivia: a retrospective study. Trans R
Soc Trop Med Hyg 1993; 87: 7-9
Ahluwalia S, Lawn SD, Grant JKH,
Lockwood DNJ. Mucocutaneous
leishmaniasis: an imported infection
among travellers to Central and South
America. BMJ 2004; 329: 842-4.
Barnetson RS, Ridley RS, Wheate HW.
A form of muco-cutaneous
leishmaniasis in the Old World. Trans R
Soc Trop Med Hyg 1978; 72: 516-8.
A1-Gindan Y, Omer AH, Al-Humaidan
Y. A case of mucocutaneous
leishmaniasis in Saudi Arabia caused by
Leishmania major and its response to
treatment. Clin Exp Dermatol 1983;
:185-8.
Sangueza OP, Sangueza JM, Stiller MJ,
Sangueza P. Mucocutaneous
leishmaniasis: a clinicopathologic
classification. J Am Acad Dermatol
; 28: 927-32
Weller PF, Durand ML, Pilch BZ. A
-year-old man with nasal congestion,
swelling, and pain. N Eng J Med 2005;
: 609-15.
Calzaa L, D'Antuono A, Marinacci G et
al. Disseminated cutaneous
leishmaniasis after visceral disease in a
patient with AIDS. J Am Acad
Dermatol 2004; 50: 461-5.
Kumar MKA; Raghunandanan SG;
Kurian CA. Mucocutaneous
leishmaniasis. Indian J Otolaryngol
Head Neck Surg 1996; 48: 238-40.
Kharfi M, Fazaa B, Chaker E, Kamoun
MR. Mucosal localization of
leishmaniasis in Tunisia: 5 cases. Ann
Dermatol Venereol 2003; 130: 27-30.