A study of comorbid conditions in psoriasis

Authors

  • Jayakar Thomas
  • N. Ashok Kumar
  • D. Manoharan
  • S. Cynthia
  • S.K. Selva Prabu
  • N. Ashwak Ahmed

DOI:

https://doi.org/10.66344/jpad.19.4.2009.544

Keywords:

Psoriasis, co morbid conditions

Abstract

Objective To study the association of psoriasis with various comorbid conditions. Patients and methods Hundred consecutive patients with psoriasis were included in the study. Complete physical examination was done. Blood pressure monitoring was done in all patients. Blood sugar (fasting), fasting lipid profile and thyroid function test were done in all patients. Results A total of 52% of patients had some comorbidity in our study. Hypertension was present in 13% while diabetes mellitus was seen in 8% of patients. Both diabetes and hypertension was seen in 12% of patients. 7% of patients were obese. Thyroid disorder and ischemic heart disease were seen in 4% of the patients each. Lipid abnormalities were seen in 4% of patients. Conclusion All patients with psoriasis should be monitored for associated comorbid conditions. For effective management of psoriasis and related comorbidities, an integrated approach targeting both cutaneous and systemic inflammation may be beneficial. 

References

Gottlieb AB, Chao C, Dann F. Psoriasis comorbidities. J Dermatolog Treat 2008; 19: 5-21.

Joshi R. Immunopathogenesis of psoriasis. Indian J Dermatol Venereol Leprol 2004; 70: 10-2.

Ayala F, Ayala F. Clinical aspects and comorbidities of psoriasis. J Rheumatol 2009; 83 (Suppl): 19-20.

Gelfand JM, Troxel AB, Lewis JD et al. The risk of mortality in patients with psoriasis: results from a population-based study. Arch Dermatol 2007; 143: 1493-9.

Krueger G, Ellis CN. Psoriasis – recent advances in understanding its pathogenesis and treatment. J Am Acad Dermatol 2005; 53: S94-100.

Henseler T, Christophers E. Disease concomitance in psoriasis. J Am Acad Dermatol 1995; 32: 982–986.

Mallbris L, Akre O, Granath F et al. Increased risk for cardiovascular mortality in psoriasis inpatients but not outpatients. Eur J Epidemiol 2004; 19: 225-30.

Sommer DM, Jenisch S, Suchan M et al. Increased prevalence of the metabolic syndrome in patients with moderate to severe psoriasis. Arch Dermatol Res 2006; 298: 321-8.

Gulliver W. Long-term prognosis in patients with psoriasis. Br J Dermatol 2008; 159: 2-9.

Christophers E. Comorbidities in psoriasis. Clin Dermatol 2007; 25: 529-34.

Gulliver W, Tomi Z, Alaghehbandan R. Prevalence of cardiovascular risk factors and other comorbidities among psoriasis patients. J Am Acad Dermatol 2007; 56 (Suppl. 2): AB191.

Downloads

Published

2016-12-24

How to Cite

1.
Thomas J, Kumar NA, Manoharan D, Cynthia S, Prabu SS, Ahmed NA. A study of comorbid conditions in psoriasis. J Pak Assoc Dermatol [Internet]. 2016Dec.24 [cited 2026Apr.12];19(4):200-2. Available from: https://www.jpad.com.pk/index.php/jpad/article/view/544

Issue

Vol. 19 No. 4 (2009): October - December

Section

Original Articles

License

Submission declaration

Authors retain the copyright to their work and grant the 'Journal of Pakistan Association of Dermatologists (JPAD)' the right of first publication under a Creative Commons Attribution 4.0 International (CC BY 4.0) license. This license allows others to share, adapt, and reuse the work for any purpose, including commercial use, as long as appropriate credit is given to the original authors and the journal.

By submitting a manuscript, authors confirm that the work has not been published previously (except as an abstract, lecture, or academic thesis), is not under review elsewhere, and has been approved by all authors and relevant authorities. Once accepted, the article will be openly accessible under the CC BY 4.0 license, ensuring wide dissemination and reuse with proper attribution.