Extramammary Paget’s disease: presenting in an unusual site

Authors

  • Kaushik Shome
  • Asit Baran Samanta
  • Saswati Halder
  • Joly Seth
  • B.K. Mandal
  • , Prodip Sarkar

DOI:

https://doi.org/10.66344/jpad.21.3.2011.474

Keywords:

Suprapubic region, Paget’s cells, cytokeratin 7, carcinoembryonic antigen

Abstract

Extramammary Paget’s disease (EMPD) is a rare neoplasm with only a limited number of reported cases in literature. It is mainly composed of intraepidermal Paget cells and possesses variable clinical behaviour and histological appearance leading to difficulty in diagnosis. We here report a case of primary EMPD in a 71-year-old male who presented with gradually progressive, pruritic, eczematous lesion in suprapubic region, not responding to topical medications. Histological assessment showed Paget cells infiltration throughout the epidermis with dermal invasion. Using immunohistochemistry, the expression of CK7, carcinoembryonic antigen (CEA) was examined to elucidate cellular differentiation of the carcinoma. 

References

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Published

2016-12-22

How to Cite

1.
Shome K, Samanta AB, Halder S, Seth J, Mandal B, Sarkar , P. Extramammary Paget’s disease: presenting in an unusual site. J Pak Assoc Dermatol [Internet]. 2016Dec.22 [cited 2026Apr.12];21(3):207-10. Available from: https://www.jpad.com.pk/index.php/jpad/article/view/474

Issue

Vol. 21 No. 3 (2011): July - September

Section

Case Reports

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