Hydroxyurea – An experience in the management of psoriasis
Keywords:
Psoriasis, hydroxyureaAbstract
Objective To assess efficacy and safety of hydroxyurea therapy in different types of psoriasis. Patients and methods Eighty patients of chronic plaque psoriasis, generalized pustular psoriasis with more than 20% body surface area and psoriatic erythroderma were included in the prospective nonrandomized study. Results At least good response (up to 50% reduction of PASI) to therapy was noticed in 77.6% (59/76), 11.9% patients did not respond and 10.5% patients worsened. Conclusion Hydroxyurea is effective in the treatment of extensive psoriasis with not so serious side effects.ÂReferences
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