Herpes-associated erythema multiforme in a child
DOI:
https://doi.org/10.66344/jpad.34.4.2024.2735Keywords:
Erythema multiforme, Herpes simplex virus, Herpes-associated EM, Pediatric, HAEMAbstract
Herpes-associated erythema multiforme (HAEM) is a syndrome of various skin eruptions triggered by previous herpes simplex virus (HSV) infection. Erythema multiforme (EM) generally attacks young adults (20-40 years) and 20% of cases occur in children. We describe a case of a 4-year-old and 6-month-old boy who presented with reddish rashes spread all over the body, especially on both legs, accompanied by fluid-filled sacs.References
Soares A, Sokumbi O. Recent updates in the treatment of erythema multiforme. Medicina (Lithuania). 2021;57(9):921.
Aurelian L, Kokuba H, Burnett JW. Understanding the pathogenesis of HSV-associated erythema multiforme. Dermatology. 1998;197(3):219-22.
Farthing P, Bagan JV, Scully C. Mucosal disease series. Number IV. Erythema multiforme. Oral Dis. 2005;11(5):261-7.
Issrani R. Etiopathogenesis of Erythema Multiforme- A Concise Review. Adv Dentist Oral Health. 2017;5(4):1-5.
Samim F, Auluck A, Zed C, Williams PM. Erythema multiforme. A review of epidemiology, pathogenesis, clinical features, and treatment. Dent Clin North Am. 2013;57:583-96.
Kokuba, Imafuku, Huang, Aurelian, Burnett. Erythema multiforme lesions are associated with the expression of a herpes simplex virus (HSV) gene and qualitative alterations in the HSV-specific T-cell response. Br J Dermatol. 1998;138(6):952-64.
Kokuba H, Aurelian L, Burnett J. Herpes simplex virus associated erythema multiforme (HAEM) is mechanistically distinct from drug-induced erythema multiforme: interferon-gamma is expressed in HAEM lesions and tumor necrosis factor-alpha in drug-induced erythema multiforme lesions. J Invest Dermatol. 1999;113(5):808-15.
Kamala K, Ashok L, Annigeri R. Herpes associated erythema multiforme. Contemp Clin Dent. 2011;2(4):372.
Mailiza, Fitria. Herpes associated erythema multiforme (HAEM): Case reports. Odonto: Dental Journal. 2022;9:33-9.
Mtiri A, Bouslama G, Messouad NB, Abidi I, Youssef SB, Sriha B. Erythema Multiforme Attributable to Herpes Simplex Virus: Clinical Aspects and Treatment. Case Rep Dent. 2021;2021:6692495.
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