Histomorphology of lichenoid tissue reactions: A retrospective study

Authors

  • Priyanka Agarwala Assistant Professor, Department of Pathology, Mahatma Gandhi University of Medical Sciences and Technology, Jaipur, India
  • Praveen Prakash Assistant Professor, Department of pathology, Rama Medical College Hospital and Research Centre, Hapur (U.P)
  • Mohit Agarwal Associate Professor, Department of Pulmonary Medicine, Mahatma Gandhi University of Medical Sciences & Technology, Jaipur
  • Sompal Singh Specialist Pathologist, Department of Pathology, Hindu Rao Hospital, Delhi, India
  • Namrata Sarin Specialist Pathologist, Department of Pathology, Hindu Rao Hospital, Delhi, India
  • Sonam Kumar Pruthi Specialist Pathologist, Department of Pathology, Hindu Rao Hospital, Delhi, India

DOI:

https://doi.org/10.66344/jpad.34.4.2024.2670

Keywords:

Histopathology, Lichenoid tissue reaction, lichen planus

Abstract

Objective To analyse variety of disorders comprising of lichenoid tissue reactions on the basis of their respective histomorphological features.   Methods A 2-year retrospective study was conducted on skin biopsies with presence of lichenoid tissue reactions. On histopathological examination, lichenoid reactions were identified in a total of 184 cases, out of which 147 were lichen planus and 37 showed lichenoid eruptions.   Results Out of the total of 184 cases, females (62.5%) were more commonly affected. Most common site of predilection being extremities (34.23%). Among the lichenoid tissue reactions, lichen planus (29.89%) and lichen planus pigmentosus (23.36%) constituted majority of cases. Presence of band-like lymphocytic infiltrate is the most constant histopathological finding of lichenoid tissue reaction followed by basal cell layer vacuolization, hyperkeratosis, hypergranulosis, acanthosis, and pigment incontinence.   Conclusion Thus, histopathology is an essential tool for reaching to a conclusive diagnosis, amongst the vast list of differential diagnosis of lichenoid tissue reactions with similar clinical presentation.  

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Published

2024-10-11

How to Cite

1.
Agarwala P, Prakash P, Agarwal M, Singh S, Sarin N, Pruthi SK. Histomorphology of lichenoid tissue reactions: A retrospective study . J Pak Assoc Dermatol [Internet]. 2024Oct.11 [cited 2026Apr.22];34(4):813-20. Available from: https://www.jpad.com.pk/index.php/jpad/article/view/2670

Issue

Vol. 34 No. 4 (2024): October-December

Section

Original Articles

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