Scarring alopecia in patients with discoid lupus erythematosus versus patients with follicular lichen planus- A comparative study of clinicopathological features

Authors

  • Khalifa E Sharquie Professor, Department of Dermatology, College of Medicine, University of Baghdad, Center of Dermatology, Medical City Teaching Hospital, Iraq
  • Mustafa Jawad Janabi Department of Dermatology, Medical City Teaching Hospital, Baghdad, Iraq

Keywords:

Discoid lupus erythematosus, Follicular lichen planus, Lichen planopilaris, Scarring alopecia, Moth eaten alopecia

Abstract

Objective To do full clinical evaluation of follicular lichen planus (lichen planopilaris) and discoid lupus erythematosus.   Methods This cross-sectional comparative work where 100 cases of scarring alopecia of scalp were included during the period from 2014-2022. Full clinical assessment including history and examination were carried out. Confirmatory blood testing and skin biopsies were done accordingly.   Results One hundred case of scarring alopecia were included in this study and subdivided in to two groups; Discoid lupus erythematosus group: included 43 cases. The pattern of hair loss was moth eaten in 10 (23.2%) cases especially in early cases. There was no well demarcated active border as the activity of the disease was almost uniform all over the patches. Follicular lichen planus group: consisted of 57 patients. The course of the disease was chronic but ranged from 4 months to three years. The pattern of hair loss was follicular moth-eaten alopecia in all cases and the clinical picture started as small moth-eaten patches and over time these small areas of alopecia were coalesced together to form large patches simulating pseudo Palade pattern of alopecia.   Conclusion Both follicular lichen planus and discoid lupus erythematosus are common causes of scarring alopecia affecting young people more in females in DLE but more in males in follicular lichen planus. The moth eaten alopecia was in all cases in patients with LPP while was detected in 23.2% of DLE patients. The prognosis of hair growth is more favorable in DLE than FLP.  

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Published

2024-10-11

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1.
Sharquie KE, Janabi MJ. Scarring alopecia in patients with discoid lupus erythematosus versus patients with follicular lichen planus- A comparative study of clinicopathological features. J Pak Assoc Dermatol [Internet]. 2024Oct.11 [cited 2026Jan.31];34(4):883-98. Available from: https://www.jpad.com.pk/index.php/jpad/article/view/2512

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