Pyoderma gangrenosum in pregnancy: a case with unusual presentat
Keywords:
Pyoderma gangrenosum, pregnancy, intralesional steroidAbstract
Pyoderma gangrenosum (PG) is an uncommon idiopathic chronic ulcerative condition, clinically characterized by initial small pustules which develop into ulcers with typical undermined borders with violaceous hue. In most cases, PG is associated with systemic diseases like inflammatory bowel disease, inflammatory polyarthritis and hematological disorders as paraproteinemia and leukemias. Diagnosis is difficult, mostly resting on the exclusion of other similar conditions, due to lack of pathognomonic histological features. We describe a case of PG in pregnancy not only for the rarity of the association, but also because of some unusual presenting features. We treated the patient by intralesional steroid injection and topical steroid application; the ulcers healed within a month.References
Brunsting LA, Goeckermann WH, O'Leary PA. Pyoderma (echthyma) gangrenosum clinical and experimental observations in five cases occurring in adults. Arch Dermatol. 1930;22: 655-80.
Powell FC, Su WP, Perry HO. Pyoderma gangrenosum: classification and management. J Am Acad Dermatol. 1996;34:395-409.
Prystowsky JH, Kahn SN, Lazarus GS. Present status of pyoderma gangrenosum. Review of 21 cases. Arch Dermatol. 1989;125:57-64.
Callen JP. Pyoderma gangrenosum: a comparison of typical and atypical forms with an emphasis on time to remission; case review of 86 patients from 2 institutions. Medicine. 2000;79:37-46.
Miller L, Yentzer BA, Clark A, et al. Pyoderma gangrenosum: a review and update on new therapies. J Am Acad Dermatol. 2010;62:646-54.
Wollina U, Haroske G. Pyoderma gangrenosum. Curr Opin Rheumatol. 2011;23:50-6.