Comparison of 5% potassium hydroxide with 10% potassium hydroxide solution in treatment of molluscum contagiosum: A comparative study
DOI:
https://doi.org/10.66344/jpad.v24i4.223Keywords:
Molluscum contagiosum, potassium hydroxide, efficacy, safetyAbstract
Objective To compare the results of 5% KOH versus 10% KOH in treatment of molluscum contagiosum (MC).
Methods 40 children having MC were divided into 2 groups. 5% KOH solution or 10% KOH solution was applied by the patient or a parent on lesions once daily for two weeks or till the appearance of inflammatory signs. Patients were followed up 2, 4, 8 and 12 weeks for efficacy and side effect. Efficacy was categorized as complete remission (³ 90% clearance of lesions), partial remission (60-90% clearance of lesions) and insignificant improvement (<60% clearance of lesions).
Results By the end of study 16 patients in group A (5% KOH) and 17 patients in group B (10% KOH) were evaluable. Partial remission was seen in 4 (25%) in group A while in group B, 7 (41.2%) patients showed complete remission and 10 (58.8%) partial remission. 100% patients in group B showed local side effect in group A and 52.3% developed local side effect in group B. The side effects were mild and did not require discontinuation of treatment.
Conclusion 10% KOH solution is more effective treatment option for molluscum contagiosum than 5% KOH solution.
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Copyright (c) 2016 Farhana Muzaffar, Farzana Faiz
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