Diffuse Large B-Cell Lymphoma with secondary cutaneous involvement

Authors

  • Praneet P. Awake Symbiosis Medical College for Women, Symbiosis International (Deemed University), Pune, Maharashtra, India
  • Anand Bhosale Department of Pathology, Symbiosis Medical College for Women, Symbiosis International (Deemed University), Pune, Maharashtra, India
  • Rajan Bindu Department of Pathology, Symbiosis Medical College for Women, Symbiosis International (Deemed University), Pune, Maharashtra, India
  • Sayali Deshmukh Department of Pathology, Symbiosis Medical College for Women, Symbiosis International (Deemed University), Pune, Maharashtra, India
  • Pallavi Chaudhari Department of Pathology, Symbiosis Medical College for Women, Symbiosis International (Deemed University), Pune, Maharashtra, India
  • Vivek Dugad Department of Pathology, Symbiosis Medical College for Women, Symbiosis International (Deemed University), Pune, Maharashtra, India

DOI:

https://doi.org/10.66344/jpad.33.1.2023.2023

Keywords:

Diffuse large B cell lymphoma, secondary cutaneous DLBCL, Non-Hodgkin’s Lymphoma

Abstract

Diffuse large B cell lymphoma (DLBCL) is an aggressive subset of Non-Hodgkin’s Lymphoma (NHL). It is composed of mature B-cells and can occur in both lymphoid and extra-lymphoid sites. Extra-nodal DLBCL is commonly observed in the gastrointestinal tract followed by the cutaneous involvement. DLBCL with cutaneous involvement can be further categorized into primary cutaneous diffuse large B-cell lymphoma (PCDLBCL) and DLBCL with secondary cutaneous involvement. We present a rare case of secondary cutaneous involvement in DLBCL in a 66-year woman.

Author Biography

Praneet P. Awake, Symbiosis Medical College for Women, Symbiosis International (Deemed University), Pune, Maharashtra, India

Dr. Praneet Awake Assistant Professor, Department of Dermatology, Venereology and Leprosy, Symbiosis Medical College for Women, Symbiosis International (Deemed University), Pune Pin:412115 Email: awakepraneet@gmail.com, p16awake@gmail.com

References

Awad M, Holzwanger E, Jubbal S. A Unique Presentation of Cutaneous Diffuse Large B-Cell Lymphoma. Case Rep Dermatol Med. 2020;2020:8310602.

Kilaru S, Panda SS, Mishra S, Mohapatra D, Baisakh M, Kolluri S, Devaraj S, Moharana L, Biswas G. Cutaneous involvement in diffuse large B cell lymphoma at presentation: report of two rare cases and literature review. J Egypt Natl Canc Inst. 2021;33(1):25.

Lee WJ, Won KH, Won CH, Chang SE, Choi JH, Moon KC, Park CS, Huh J, Suh C, Lee MW. Secondary Cutaneous Diffuse Large B-cell Lymphoma has a Higher International Prognostic Index Score and Worse Prognosis Than Diffuse Large B-cell Lymphoma, Leg Type. Acta Derm Venereol. 2016;96(2):245-50.

Lloret-Ruiz C, Molés-Poveda P, Barrado-Solís N, Gimeno-Carpio E. Linfoma B difuso de células grandes sistémico con afectación cutánea secundaria. Actas Dermosifiliogr. 2015;106:685-7.

Magro CM, Wang X, Subramaniyam S, Darras N, Mathew S. Cutaneous double-hit B-cell lymphoma: An aggressive form of B-cell lymphoma with a propensity for cutaneous dissemination. Am J Dermatopathol. 2014;36:303-10.

Ferrão JB, Barreira JV, Marote S, Parmanande A. Diffuse large B cell lymphoma: cutaneous presentation. BMJ Case Rep. 2018;11(1):e226839.

Takahashi H, Tomita N, Yokoyama M, Tsunoda S, Yano T, Murayama K, et al. Prognostic impact of extranodal involvement in diffuse large B-cell lymphoma in the rituximab era. Cancer. 2012;118(17):4166-72.

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Published

2023-03-05

How to Cite

1.
Awake PP, Bhosale A, Bindu R, Deshmukh S, Chaudhari P, Dugad V. Diffuse Large B-Cell Lymphoma with secondary cutaneous involvement. J Pak Assoc Dermatol [Internet]. 2023Mar.5 [cited 2026Apr.12];33(1):294-7. Available from: https://www.jpad.com.pk/index.php/jpad/article/view/2023

Issue

Vol. 33 No. 1 (2023): January-March

Section

Case Reports

License

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