A case series of atypical cutaneous malignancies in dermatology out-patient department in a tertiary care centre of eastern India

Authors

  • Partha Sarathi Nayak Medical College Kolkata
  • Assistant Professor Medical College Kolkata
  • Senior Resident Medical College Kolkata
  • Senior Resident Medical College Kolkata
  • Junior Resident Medical College Kolkata
  • Junior Resident Medical College Kolkata
  • Professor & HOD Medical College Kolkata

DOI:

https://doi.org/10.66344/jpad.v32i2.1906

Abstract

The skin being a dynamic organ with multiple components, lead to malignancies of an extended spectrum. Keratinocytes, melanocytes and even the endothelial cells may turn malignant. Incidence of skin cancers has been on the rise since the last few decades worldwide. The focus has been mainly on the commonly encountered malignancies like the squamous cell carcinoma (SCC), basal cell carcinoma (BCC) and melanoma. However, certain atypical skin tumors and certain atypical presentation of the common tumors can be quite challenging clinically. Skin tumors may also be a combination of the typical ones. Malignant cutaneous appendageal tumors are quite rare and vascular tumors like hemangioendothelioma are often a forgotten entity. We have encountered four interesting atypical malignancies in our outpatient clinic which include a basosquamous carcinoma of the scalp, porocarcinoma of the hand, epithelioid hemangioendothelioma of the lower limb, and a morpheaform BCC in the neck. Knowledge about the above discussed four cases are required, so that they are not missed. 

References

1. De Faria .Basal cell carcinoma of the skin with areas of squamous cell carcinoma: a basosquamous cell carcinoma. J Clin Pathol. 1985;38(11):1273-7.

2. Weedon D. Skin Pathology. London: Churchill Livingstone; 2002. p. 1158.

3. Leibovitch I, Huilgol SC, Selva D, et al. Basosquamous carcinoma: treatment with Mohs micrographic surgery. Cancer. 2005;104(1):170-5.

4. Bowman PH, Ratz JG, Knoepp TG, et al. Basosquamous carcinoma. Dermatol Surg. 2003;29:830-3.

5. Sendur N, Karaman G, Dikicioglu E, et al. Cutaneous basosquamous carcinoma infiltrating cerebral tissue. J Eur Acad Dermatol Venereol. 2004;18:334-6.

6. Garcia C, Poletti E, Crowson AN. Basosquamous carcinoma. J Am Acad Dermatol. 2009;60:137-43.

7. Martin RC 2nd, Edwards MJ, Cawte TG, et al.Basosquamous carcinoma: analysis of prognostic factors influencing recurrence. Cancer. 2000;88(6):1365-9.

8. Elder DE, Elenitsas R, Johnson BL, Murphy GF, editors. Vascular tumors: Tumors and tumor-like conditions of blood vessels and lymphatics. In: Lever's Histopathology of the Skin. 10th ed. Philadelphia: Wolters Kluwer; 2009. p. 1039-42.

9. Dail DH, Liebow AA. Intravascular bronchioloalveolar tumor. Am J Pathol. 1975;78:6a-7a.

10. Sardaro A, Bardoscia L, Petruzzelli MF, et al. Epithelioid hemangioendothelioma: An overview and update on a rare vascular tumor. Oncol Rev. 2014;8:259.

11. Park SM, Kim HS, Ko HC, et al. Cutaneous epithelioid hemangioendothelioma treated with Mohs micrographic surgery. Int J Dermatol. 2017;56:97-9.

12. Kikuchi K, Watanabe M, Terui T, et al. Nail-destroying epithelioid haemangioendothelioma showing an erythematous scar-like appearance on the finger. Br J Dermatol. 2003;148:834-6.

13. Forschner A, Harms D, Metzler G, et al. Ulcerated epithelioid hemangio-endothelioma of the foot in childhood. J Am Acad Dermatol. 2003;49:113-6.

14. Kim JW, Oh DJ, Kang MS, et al. A case of metastatic eccrine porocarcinoma. Acta DermVenereol. 2007;87:550-2.

15. Bhat W, Akhtar S, Khotwal A, et al. Primary eccrine porocarcinoma of the finger with transit forearm and axillary metastasis. Ann Plast Surg. 2011;66:344-6.

16. Song SS, Wu Lee W, Hamman MS, Jiang SI. Mohs micrographic surgery for eccrine porocarcinoma: An update and review of the literature. Dermatol Surg. 2015;41:301-6.

17. Brown CW Jr., Dy LC. Eccrine porocarcinoma. Dermatol Ther. 2008;21:433-8.

18. Sharathkumar HK, Hemalatha AL, Ramesh DB, Soni A, Revathi V. Eccrine porocarcinoma: A case report. J Clin Diagn Res. 2013;7:2966-7.

19. Sgouros D, Piana S, Argenziano G, Longo C, Moscarella E, Karaarslan IK, et al. Clinical, dermoscopic and histopathological features of eccrine poroid neoplasms. Dermatology. 2013;227:175-9.

20. Johr R, Saghari S, Nouri K. Eccrine porocarcinoma arising in a seborrheic keratosis evaluated with dermoscopy and treated with Mohs' technique. Dermatol Surg. 2003;42:653-7.

21. Walling HW, Fosko SW, Geraminejad PA, et al. Aggressive basal cell carcinoma: presentation, pathogenesis, and management. Cancer Metastasis Rev. 2004;23:389–402.

22. Rubin AI, Chen EH, Ratner D. Basal-cell carcinoma. N Engl J Med. 2005;353:2262-9.

23. Scrivener Y, Grosshans E, Cribier B. Variations of basal cell carcinomas according to gender, age, location and histopathological subtype. Br J Dermatol. 2002;147(1):41-7.

24. Calonje E, McKee PH. McKee’s Pathology of the Skin: With Clinical Correlations. Philadelphia, PA: Elsevier/Saunders; 2012.

Downloads

Published

01.06.2022

Issue

Section

Case Reports

How to Cite

1.
A case series of atypical cutaneous malignancies in dermatology out-patient department in a tertiary care centre of eastern India. J Pak Assoc Dermatol [Internet]. 2022 Jun. 1 [cited 2026 Sep. 6];32(2):414-20. Available from: https://www.jpad.com.pk/index.php/jpad/article/view/1906