Squamous Cell Carcinoma in Epidermolysis bullosa (dystrophic)

Authors

  • Irfan Ahmed Sheikh SMBBMU, Larkana,
  • Naeem Ahmed Department of Dermatology, Shaheed Mohtarma Benazir Bhutto Medical University, Larkana.
  • Kaiser Jatoi Department of Dermatology, Shaheed Mohtarma Benazir Bhutto Medical University, Larkana.

DOI:

https://doi.org/10.66344/jpad.v31i3.1867

Abstract

Epidermolysis bullosa are heterogeneous group of rare diseases characterized by exacerbated skin and mucosal fragility and blister formation after minor trauma. This family of genodermatosis exposes patients to several complications, Cutaneous SCC being most severe. We present a case of 19 years old patient of Squamous cell carcinoma in Epidermolysis bullosa of right foot treated with surgery and radiotherapy.

Author Biography

  • Irfan Ahmed Sheikh, SMBBMU, Larkana,

    Associate Professor,
    Department of Dermatology,

References

1. Fine JD, Johnson LB, Weiner M et al. Epidermolysis bullosa and the risk of life threatning cancers: national EB registry experience, 1986-2006. J Am Acad Dermatol.2009;60:203-11.

2. Fine JD, Johnson LB, Suchindran C, Bauer EA, Carter M,McGuire J, et al. Cancer and inherited epidermolysis bullosa. In: Fine J, Bauer E, McGuire J, Moshell A, eds. Epidermolysis bullosa. Baltimore, MD: The Johns Hopkins University Press.1999:175–92

3. Fine JD, Johnson LB, Suchindran C, Bauer EA, Carter M. McGuire J, et al. Premature death and inherited epidermolysis bullosa. In: Fine J, Bauer E, McGuire J, Moshell A, eds. Epidermolysis bullosa. Baltimore, MD: The Johns Hopkins University Press.1999: 207–24.

4. Mseddi M, Turki H, Marrekchi S et al. Squamous cell carcinomacomplicating a hereditary epidermolysis bullosa. Cancer Radiother.2004;8:266–9. (in French).

5. Chuang TY. Skin cancer II: nonmelanoma skin cancer. In: Williams HC, Strachan DP, eds. The challenge of dermato epidemiology. New York: CRC Press, 1997: 209-22

6. Souza CS, Fel_ ıcio LB, Bentley MV et al. Topical photodynamic therapyfor Bowen’s disease of the digit in epidermolysis bullosa. Br Dermatol.2005;153:672

7. Song IC, Dicksheet S. Management of squamous cell carcinoma in a patient with dominant-type epidermolysis bullosa dystrophica: a surgical challenge. Plast Reconstr Surg.1985;75:732–6.

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Published

10.04.2022

Issue

Section

Case Reports

How to Cite

1.
Squamous Cell Carcinoma in Epidermolysis bullosa (dystrophic). J Pak Assoc Dermatol [Internet]. 2022 Apr. 10 [cited 2026 Sep. 11];31(3):553-5. Available from: https://www.jpad.com.pk/index.php/jpad/article/view/1867