Papillon-Lefèvre syndrome: A case report of two siblings and review of the literature
DOI:
https://doi.org/10.66344/jpad.v24i1.182Keywords:
periodontitis, palmoplantar keratoderma, Papillon-Lefèvre syndromeAbstract
Papillon-Lefèvre syndrome is a rare autosomal recessive genodermatosis which is characterised by periodontitis, palmoplantar keratoderma and predisposition to pyogenic infections and occurs due to cathepsin C gene mutation (located on chromosome11).The loss of primary teeth usually occurs by the age of 4 years and secondary teeth by second decade. The disorder is associated with significant cosmetic and functional disability.
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Copyright (c) 2016 Peerzada Sajad, Iffat Hassan, Syed Imtiyaz
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