Treatment of Multiple Cutaneous Leishmaniasis Lesions in Diabetic Patient with Photodynamic Therapy

Treatment of Multiple CL Lesions in Diabetic Patient with PDT

Abstract

Cutaneous leishmaniasis (CL) is the most common type of leishmaniasis. It is originated by different species of the protozoan parasite leishmania, transmitted by infected female sand flies. Although CL is not life-threatening, still may leavequite disfiguring and ugly scars on infected areas. In this case report,we detail the case of asixty-five-year-old diabetic male patient with CL, associated with multiple chronic disfiguring ulcers on foot, ear, leg and arm. The patient was successfully treated with methyl aminolevulinatebased photodynamic therapy (PDT) and after 5 sessions, complete response was achieved.The patient was followed with excellent cosmetic outcome, with no recurrence throughout the observation time and no complication was observed. This study demonstrates the promising role of PDT in the treatment of CL. We have formulated photosensitizer through our institute developed protocol, which increase its efficacy and bring down the medicine cost from US$ 500 to US$ 50.