A generalized, pruritic, papulo-vesicular eruption in an infant: An uncommon presentation of Gianotti Crosti Syndrome

Authors

  • Jaspriya Sandhu Dayanand Medical College& hospitalLudhiana, PunjabIndia 141001
  • Shriya Garg Department of Dermatology, Venereology & Leprosy, DMCH, Ludhiana, Punjab, India
  • Sunil Gupta Department of Dermatology, Venereology & Leprosy, DMCH, Ludhiana, Punjab, India
  • Bhavna Garg Department of Pathology, DMCH, Ludhiana, Punjab, India

DOI:

https://doi.org/10.66344/jpad.v31i4.1746

Abstract

A 1-year- old boy was brought by his parents with a 2-week-history of skin colored to erythematous crusted, papulo-vesicles distributed symmetrically over face, extremities and prominent truncal involvement. Lesions were intensely pruritic, disrupting the child’s sleep; an episode of upper respiratory tract infection (URTI) preceded the eruption. A skin biopsy was done keeping the differential of Gianotti Crosti Syndrome (GCS), histiocytosis and pityriasis lichenoides et varioliformis acuta (PLEVA); epidermis showed acanthosis, hyperkeratosis and follicular plugging, with scant perivascular lymphocytic infiltrate in the dermis. Emollients, topical steroids and antihistamines led to marked improvement at 1-week follow-up; on clinico-pathological correlation, a diagnosis of an Atypical GCS was made. To the best of our knowledge, such an atypical presentation of GCS has not been previously reported.

References

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Published

29.03.2022

How to Cite

1.
A generalized, pruritic, papulo-vesicular eruption in an infant: An uncommon presentation of Gianotti Crosti Syndrome. J Pak Assoc Dermatol [Internet]. 2022 Mar. 29 [cited 2026 Aug. 1];31(4):720-4. Available from: https://www.jpad.com.pk/index.php/jpad/article/view/1746