Spectrum of skin menifestations in patients presenting with idiopathic thrombocytopenic purpura in a tertiary care hospital
Keywords:
Idiopathic thrombocytopenic purpura, thrombocytopenia, skin manifestationsAbstract
Introduction Idiopathic thrombocytopenic purpura (ITP) is defined as a hematologic disorder, characterized by isolated thrombocytopenia without a clinically apparent cause; it is considered to be a diagnosis of exclusion. The clinical presentation may be acute with severe bleeding, or insidious with mild or no symptoms. Objectives The aim of this retrospective study was to measure the presenting features and clinical characteristics of ITP in the Hematology department of Lahore General Hospital Lahore, a tertiary care hospital in collaboration with medical department. Methods 96 patients who were diagnosed with ITP on bone marrow biopsy, in Department of Hematology, Lahore General Hospital between January, 2017 and December, 2019 were selected. Age of the patients, gender, presenting complaints and laboratory tests were recorded. Results Mean Age of the patients on diagnosis was between 2-60 years. The female: male ratio came out to be 2.09:1. The most frequent complaint was found to be petechiae on the skin (31.25%), followed by bruises, bleeding gums, epistaxis and nasal bleed. Conclusion ITP was found to be most common in females less than 20 years of age and skin manifestations were observed to be the most frequent presenting complaints.ÂReferences
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