Bathing trunk nevus with multiple satellite lesions and neuroid proliferations
DOI:
https://doi.org/10.66344/jpad.31.2.2021.1558Keywords:
Giant congenital melanocytic nevus, neuroid proliferations, satellite lesionsAbstract
Giant congenital melanocytic nevus (GCMN) are rare melanocytic proliferations of the skin. These may be associated with benign neuroid proliferations, lipomas and abnormalities such as spina bifida. Major concern with GCMN is risk of neurocutaneous melanosis (NCM), melanoma, or other complications. We report a case of a 4- year-old girl with an extensive hyperpigmented plaque that covered her entire trunk involving almost 50% of her body surface area, highly suggestive of a giant congenital melanocytic nevus. Multiple neuroid proliferations were present. ÂReferences
Tannous Z, Mihm MJ, Sober A, Duncan L. Congenital melanocytic nevi: clinical and histopathologic features, risk of melanoma, and clinical management. J Am Acad Dermatol. 2005;52:197–203.
Alper JC, Holmes LB. The incidence and significance of birthmarks in a cohort of 4,641 newborns. Pediatr Dermatol 1983;1:58–68.
Castilla EE, da Graça Dutra M, Orioli-Parreiras IM. Epidemiology of congenital pigmented naevi: I. Incidence rates and relative frequencies. Br J Dermatol. 1981;104:307–315.
Papp T, Pemsel H, Zimmermann R et al Mutational analysis of the Nâ€ras, p53, p16INK4a, CDK4, and MC1R genes in human congenital melanocytic naevi. J Med Genet 1999; 36:610–14.
DeDavid M, Orlow SJ, Provost N, Marghoob AA, Rao BK, Huang CL, et al. A study of large congenital melanocytic nevi and associated malignant melanomas: review of cases in the New York University Registry and the world literature. J Am Acad Dermatol. 1997;36:409–416.
Dawson HA, Atherton DJ, Mayou B. A prospective study of congenital melanocytic naevi: progress report and evaluation after 6 years. Br J Dermatol. 1996;134:617–623.
From L. Congenital nevi--let's be practical. Pediatr Dermatol. 1992;9:345–346.
Hale E, Stein J, Ben-Porat L, Panageas K, Eichenbaum M, Marghoob A, et al. Association of melanoma and neurocutaneous melanocytosis with large congenital melanocytic naevi--results from the NYU-LCMN registry. Br J Dermatol. 2005;152:512–517.
Mc Kie RM. Disorders of the cutaneous melanocyte. In: Burns T, Breathnach S, Cox N, Griffiths C, editors. Rook's Textbook of Dermatology.7 th ed. London: Blackwell Science 2004;38:18-38.20.
Habib A, Razieh SA, Darius M, Nasrin S, Payam S. Giant congenital melanocytic nevus with neurofibroma-like changes and spina bifida occulta. Int J Dermatol 2006;45:1347-50.
Gulati R, Jain D, Mehrania K, Chitarmal K, Mathur D. Giant congenital nevomelanocytic nevus with satellite lesions, vitiligo and lipoma: A rare association. Indian J Dermatol Venereol Leprol 2000;66:316-7.
Kinsler VA, O'Hare P, Bulstrode N, et al. Melanoma in congenital melanocytic naevi. Br J Dermatol. 2017;176:1131â€1143. doi:10.1111/bjd.15301
Krengel S, Scope A, Dusza SW, Vonthein R, Marghoob AA. New recommendations for the categorization of cutaneous features of congenital melanocytic nevi. J Am Acad Dermatol. 2013;68:441-451.
Downloads
Published
How to Cite
Issue
Section
License
Submission declaration
Authors retain the copyright to their work and grant the 'Journal of Pakistan Association of Dermatologists (JPAD)' the right of first publication under a Creative Commons Attribution 4.0 International (CC BY 4.0) license. This license allows others to share, adapt, and reuse the work for any purpose, including commercial use, as long as appropriate credit is given to the original authors and the journal.
By submitting a manuscript, authors confirm that the work has not been published previously (except as an abstract, lecture, or academic thesis), is not under review elsewhere, and has been approved by all authors and relevant authorities. Once accepted, the article will be openly accessible under the CC BY 4.0 license, ensuring wide dissemination and reuse with proper attribution.