General paresis of the insane - A rare case report

Authors

  • Seethalakshmi Ganga vellaisamy Associate professor, Dept.of skin and STD Vinayaka missions kirupananda variyar medical college & hospital, Salem-636308 Tamil nadu India
  • Subramania Adityan Murugan Subramania Adityan Murugan, MBBS, MD(DVL) Consultant Dermatologist Adityan Skin and Laser Center, 21 B, T.P.K. Road, Andalpuram Madurai-625003,Tamilnadu, India Mobile number: 91-8012000000 adityan.ms@gmail.com

DOI:

https://doi.org/10.66344/jpad.v30i1.1367

Keywords:

General paresis of insane, crystalline penicillin, lumbar puncture

Abstract

General Paresis of the Insane (GPI) is a meningoencephalitis as a result of direct invasion of Treponema pallidum into the cerebrum, typically develops between 15 and 20 years after initial infection. Mr. X is a 50 year old painter referred to Venereology Department from Neurology Department with 3 years history of gradually progressive behavioural disturbances along with disturbances in speech & difficulty in writing. Blood VDRL & CSF VDRL was found to be reactive. A diagnosis of GPI was made and the patient was treated appropriately. He showed remarkable improvement following treatment.

Author Biographies

  • Seethalakshmi Ganga vellaisamy, Associate professor, Dept.of skin and STD Vinayaka missions kirupananda variyar medical college & hospital, Salem-636308 Tamil nadu India

    Associate professor,

    Dept.of skin and STD,


    Vinayaka missions kirupananda variyar medical college & hospital

  • Subramania Adityan Murugan, Subramania Adityan Murugan, MBBS, MD(DVL) Consultant Dermatologist Adityan Skin and Laser Center, 21 B, T.P.K. Road, Andalpuram Madurai-625003,Tamilnadu, India Mobile number: 91-8012000000 adityan.ms@gmail.com

    Subramania Adityan Murugan, MBBS, MD(DVL)
    Consultant Dermatologist
    Adityan Skin and Laser Center,
    21 B, T.P.K. Road, Andalpuram
    Madurai-625003,Tamilnadu, India
    Mobile number: 91-8012000000
    adityan.ms@gmail.com

References

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Published

07.08.2020

Issue

Section

Case Reports

How to Cite

1.
General paresis of the insane - A rare case report. J Pak Assoc Dermatol [Internet]. 2020 Aug. 7 [cited 2026 Jul. 22];30(1):203-6. Available from: https://www.jpad.com.pk/index.php/jpad/article/view/1367