Multiple autoimmune syndrome with isotopic phenomenon: association of lichen planus, vitiligo and alopecia areata with autoimmune hepatitis

Authors

  • Smitha S Prabhu Dept. of Dermatology Kasturba Medical College Manipal. Karnataka, India
  • Deepthi Ravi KMC,. Manipal
  • Shrutakirthi Damodar Shenoi KMC, Manipal
  • Kanthilatha Pai KMC, Manipal
  • Sudhir UK Nayak Dept. of Dermatology, KMC, Manipal

DOI:

https://doi.org/10.66344/jpad.28.3.2018.1131

Keywords:

Multiple autoimmune syndrome, lichen planus, vitiligo, alopecia areata, isotopic phenomenon

Abstract

Multiple autoimmune syndrome (MAS) is the presence of 3 or more autoimmune disorders in the same patient, and is being increasingly reported.  Here, we report a 31-year-old man who presented with lichen planus, vitiligo, alopecia areata and hepatitis. He also displayed isotopic phenomenon in the form of depigmented lichen planus lesions. Autoimmune tautology is implicated as the basis for  MAS, and is supported by the findings of polyautoimmunity and familial immunity in cross-sectional studies. There are reports of dermatological and systemic autoimmune diseases co-occurring as MAS. 

Author Biographies

Smitha S Prabhu, Dept. of Dermatology Kasturba Medical College Manipal. Karnataka, India

Associate ProfessorDept. of Dermatology & Dermatology & VenereologyKasturba Medical College, Manipal

Deepthi Ravi, KMC,. Manipal

Junior Resident (Ex)Dept. of DermatologyKasturba Medical CollegeManipal.Karnataka, India

Shrutakirthi Damodar Shenoi, KMC, Manipal

ProfessorDept. of DermatologyKasturba Medical CollegeManipal.Karnataka, India

Kanthilatha Pai, KMC, Manipal

Professor and HeadDept. of PathologyKasturba Medical CollegeManipal.Karnataka, India

Sudhir UK Nayak, Dept. of Dermatology, KMC, Manipal

Associate Professor  Dept. of DermatologyKasturba Medical CollegeManipal.Karnataka, India

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Published

2018-12-13

How to Cite

1.
Prabhu SS, Ravi D, Shenoi SD, Pai K, Nayak SU. Multiple autoimmune syndrome with isotopic phenomenon: association of lichen planus, vitiligo and alopecia areata with autoimmune hepatitis. J Pak Assoc Dermatol [Internet]. 2018Dec.13 [cited 2026Apr.22];28(3):363-6. Available from: https://www.jpad.com.pk/index.php/jpad/article/view/1131

Issue

Vol. 28 No. 3 (2018): July - September

Section

Case Reports

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