Frequency of various dermatoses requiring histopathological evaluation for definitive diagnosis
DOI:
https://doi.org/10.66344/jpad.v34i4(Suppl).2830Keywords:
dermatoses, histopathology, dermatopathology, psoriasis, dermatitisAbstract
Objective To assess the frequency of different dermatoses in patients undergoing biopsy for a definitive diagnosis at a tertiary care hospital.
Methods A total of 352 patients of both genders (who required biopsy for definitive diagnosis), 12 to 70 years of age were included. Patients with previous history of radiotherapy and chemotherapy were excluded. Biopsy was performed after taking consent from the patient or the guardian. Detailed examination of skin was performed for each patient, histopathological evaluation was done and recorded on predesigned proforma (attached). Frequency of various dermatoses were recorded as per-operational definition.
Results Frequency of eczema dermatitis was found in 115 (32.67%) patients, papulosquamous disorders like psoriasis in 27 (7.67%), Infectious skin diseases like leishmania in 22 (38.54%), drug reaction in 18 (5.11%) and others diagnosis in 170 (48.30%) patients.
Conclusion This study concluded that there should be early recognition and management of these disease in order to improve the quality of life of these particular patients.
References
1. Hay RJ, Johns NE, Williams HC, Bolliger IW, Dellavalle RP, Margolis DJ, et al. The global burden of skin disease in 2010: An analysis of the prevalence and impact of skin conditions. J Invest Dermatol. 2014;134(6):1527–34.
2. Azam F, Munir S, Ashraf A, Imran AA, Rashid T. Histopathological analysis of skin biopsies in a tertiary care setting. J Pak Assoc Dermatol. 2018;27(2):154-7.
3. Kayhan M, Unluoglu I, Kayhan S, Bilge U. Assessment of clinical diagnosis, age and gender differences of elderly patients applying to dermatology clinic of a secondary health institute in family medicine aspect. Biomed Res. 2017;28:2.
4. Patel K, Desai B. Pediatric dermatoses encountered in dermatology outpatient department of a teaching institute. Int J Contemp Pediatr. 2016;3(4):1178–84. Available from: http://www.ijpediatrics.com
5. Aman S, Nadeem M, Mahmood K, Ghafoor MB. Pattern of skin diseases among patients attending a tertiary care hospital in Lahore, Pakistan. J Taibah Univ Med Sci. 2017;12(5):392–6. Available from: /pmc/articles/PMC6694895/
6. Korfitis C, Gregoriou S, Antoniou C, Katsambas AD, Rigopoulos D. Skin biopsy in the context of dermatological diagnosis: a retrospective cohort study. Dermatol Res Pract. 2014;2014:734906.
doi: 10.1155/2014/734906.
7. Weinstein DA, Konda S, Coldiron BM. Use of skin biopsies among dermatologists. Dermatologic Surg. 2017;43(11):1348–57.
8. Rosenbaum BE, Klein R, Hagan PG, Seadey MY, Quarcoo NL, Hoffmann R, Robinson M, Lartey M, Leger MC. Dermatology in Ghana: a retrospective review of skin disease at the Korle Bu Teaching Hospital Dermatology Clinic. Pan Afr Med J. 2017;26:125.
9. Ahmed I, Ansari M, Malick K. An audit of dermatoses at Baqai Institute of Skin Diseases, Karachi. J Pak Assoc Dermatol. 2017;13(3):117-22.
10. Javed M, Jairamani C. Pediatric dermatology: An audit at Hamdard University Hospital, Karachi. J Pak Assoc Dermatol. 2006;16(2):93–6.
11. Definition of Skin biopsy [Internet]. [cited 2021 May 1]. Available from: https://www.medicinenet.com/skin_biopsy/definition.htm
12. Nischal U, Nischal KC, Khopkar U. Techniques of skin biopsy and practical considerations. J Cut Aesthet Surg. 2008;1(2):107.
13. Ramsey ML, Rostami S. Skin biopsy. StatPearls [Internet]. 2020 Jan 7.
14. Yang S, Kampp J. Common Dermatologic Procedures. Med Clin North Am. 2015;99(6):1305-21.
15. Korftis C, Gregoriou S, Antoniou C, Katsambas AD, Rigopoulos D. Skin biopsy in the context of dermatological diagnosis: a retrospective cohort study. Dermatol Res Pract. 2014; 2014:734906.
16. Venugopal R, Shankar P, Pathania V. Clinicopathological correlation in the diagnosis of skin diseases: A retrospective study. Medical Journal of Dr. DY Patil Vidyapeeth. 2020;13(6):648.
17. Rao GS, Kumar SS, Sandhya Pattern of skin diseases in an Indian village. Indian J Med Sci. 2003;57:108–10.
18. Alghanmi NM, Abdullah LS. Pathology of skin diseases. A study from Western Saudi Arabia. Saudi Med J. 2012;34:74–9.
Downloads
Published
Issue
Section
License
Copyright (c) 2024 Hina Ehsan, Saadiya Siddiqui; Hira Aslam, Saima Dustgir; Ramla Kazmi; Faria Altaf, Hira Tariq; Shahbaz Aman

This work is licensed under a Creative Commons Attribution 4.0 International License.
Submission declaration
Authors retain the copyright to their work and grant the 'Journal of Pakistan Association of Dermatologists (JPAD)' the right of first publication under a Creative Commons Attribution 4.0 International (CC BY 4.0) license. This license allows others to share, adapt, and reuse the work for any purpose, including commercial use, as long as appropriate credit is given to the original authors and the journal.
By submitting a manuscript, authors confirm that the work has not been published previously (except as an abstract, lecture, or academic thesis), is not under review elsewhere, and has been approved by all authors and relevant authorities. Once accepted, the article will be openly accessible under the CC BY 4.0 license, ensuring wide dissemination and reuse with proper attribution.






