Biochemical proï¬le in patients of hirsutism presenting in outpatient department of Combined Military Hospital, Jhelum and Combined Military Hospital, Kharian
Keywords:
Hirsutism, Polycystic ovarian syndrome, TestosteroneAbstract
Introduction Hirsutism is a common distressing disease and a frequent reason for dermatological consultation. Although hirsutism is prevalent worldwide, not many studies have been done in Pakistan. A cross sectional study was carried out in Dermatology department of combined military hospital (CMH) Jhelum from 15th March 2019 to 14th September 2019 to find out hormonal and radiological changes in patients reporting with complaint of hirsutism. Â Methods 140 females presenting with hirsutism, in the age group of 18 till 50 years were recruited in the study. All Pregnant women, lactating mothers and women taking oral contraceptive pills, oral hypoglycemic, anti-androgen drugs were excluded from the study. Assessment of hirsutism was done by means of Ferriman-Gallwey scoring system. Patients were called on second to third day of menstrual cycle and samples were collected after an overnight medical fasting of 10-12hrs. The patients on the 2nd or 3rd day of menstrual cycle all had their blood tests (LH: FSH, Prolactin and Testosterone) along with ultrasound of ovaries and adrenals. Â Results Frequency of hormonal and radiological findings in patients presenting with hirsutism were Polycystic ovarian syndrome 71 (50.71%), adrenal mass in none (0.0%) patients, Raised LH: FSH ratio in 13 (9.29%), raised total testosterone in 28 (20.0%), hyperprolactinemia in 09 (6.43%) and those without any cause was 19 (13.57%). Â Conclusion The most frequent cause of hirsutism was polycystic ovarian syndrome and subsequently idiopathic hirsutism. ÂReferences
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