Efficacy of micro-needling in patients of localized vitiligo: A single group clinical trial
Keywords:
Localized vitiligo, Micro-needling, efficacyAbstract
Objective To ascertain the effectiveness of micro needling in tertiary care patients with localised vitiligo. Methods It was a single group clinical trial conducted at Dermatology Department of Nishtar Medical University, Multan. Local anaesthetic was injected into the chosen vitiligo lesions while adhering to aseptic precautions. Next, dermapen micro needling was performed very slowly, with needle penetrating depths varying from 0.25 to 0.5 mm over the face and 1 to 2 mm over the body in both directions (horizontal and vertical), until the end-point of pin point bleeding. Results Of total 111 study cases, 45 (40.5%) were males while 66 (59.5%) were females. Patients had a mean age of 27.91±9.49 years. Family history of vitiligo was positive in 22 (19.8%) of our study cases and 45 (40.5%) were married while 66 (59.5%) were unmarried. Of these 111 study cases, efficacy was seen in 81 (73.0%) of patients. Conclusion Results of this study use of micro-needling in localized vitiligo, as it was found highly effective, safe and reliable in the targeted population. No adverse events were encountered among study cases and efficacy of micro-needling was significantly dependent upon disease duration. Physicians treating these patients can effectively employ micro-needling for treating localized vitiligo to achieve desired clinical outcomes to relieve these patients from psycho – social stress.References
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