Clinical audit: Baseline investigations for intramuscular meglumine antimoniate in cases of cutaneous leishmaniasis
Keywords:
Clinical audit, meglumine antimoniate, cutaneous leishmaniasisAbstract
Objectives To see if the baseline investigations for intramuscular meglumine antimoniate in cases of cutaneous leishmaniasis were being carried out in accordance to our local guidelines. Patients and methods 30 case records of patients with cutaneous leishmaniasis were randomly selected from our dermatology ward. These records were reviewed to see if the pre-therapy investigations for meglumine antimoniate were carried out. The method of data collection was retrospective. Results The result showed 100% compliance with our local guidelines in the analyzed cases. Conclusion Our audit showed 100% compliance.References
Hepburn NC. Cutaneous leishmaniasis. Clin Exp Dermatol. 2000;25:363-70.
Ejaz A, Raza N, Din QU, Bux H. Outbreak of cutaneous leishmaniasis in Somniani, Balochistan – implementation of preventive measures for deployed personnel of armed forces. J Pak Assoc Dermatol. 2008;18:220-5.
Nilforoushzadeh MA, Sadeghian G, eds. Cutaneous leishmaniasis. Isfahan: Isfahan University of Medical Sciences Publication; 2002. p. 114-6.
Conizares O, editor. The Leishmaniasis. Clinical Tropical Dermatology. Oxford: Blackwell Scientific Publication; 1975. P. 185-204.
Badaro R, Falcoff E, Badaro FS et al. Treatment of visceral leishmaniasis with pentavalent antimony and interferon gamma. NEJM. 1990;322:16-21.
Oumeish OY. Cutaneous leishmaniasis: a historical perspective. Clin Dermatol. 1999;17:249-54.
Sharma RC, Mahajan VK, Sharma NL, Sharma A. A new focus of cutaneous leishmaniasis in Himachal Pradesh (India). Indian J Dermatol Venereol Leprol. 2003;69:170-2.
Kolaczinski J, Brooker S, Reyburn H, Rowland M. Epidemiology of anthroponotic cutaneous leishmaniasis in Afghan refugee camps in northwest Pakistan. Trans R Soc Trop Med Hyg. 2004;98:373-8.
Bhutto AM, Soomro RA, Nonaka S, Hashiguchi Y. Detection of new endemic areas of cutaneous leishmaniasis in Pakistan: a 6-year study. Int J Dermatol. 2003;42:543-8.
Brooker S, Mohammed N, Adil K et al. Leishmaniasis in refugee and local Pakistani populations. Emerg Infect Dis. 2004;10:1681-4.
Khatami A, Firooz A, Gorouhi F, Dowlati Y. Treatment of acute Old World cutaneous leishmaniasis: A systematic review of the randomized controlled trials. J Am Acad Dermatol. 2007;57:335.e1-29.
Herwaldt BL, Berman JD. Recommendations for treating leishmaniasis with sodium stibogluconate (Pentostam) and review of pertinent clinical studies. Am J Trop Med Hyg. 1992;46:296-306.
Neva F, Sacks D, editors. Tropical and Geographical Medicine. 2nd edition. New York: McGraw-Hill; 1990. P. 296-307.
Harman PRM. Leishmaniasis. In: Rock A, Wilkinson DS, Ebling FJO, eds. Textbook of Dermatology. Oxford: Blackwell Scientific publications; 1979. P. 901-4.
Chulay JD, Spencer HC, Mugambi M. Electrocardiographic changes during treatment of leishmaniasis with pentavalent antimony J Trop Med Hyg. 1985;34:702-9.
Marintclle C. The control of leishmaniasis. Bull WHO. 1980:58:807-18.
de Lalla F, Pellizer G, Gradoni L et al. Acute pancreatitis associated with the administration of meglumine antimonate. Clin Infect Dis. 1993;16;730-1.
Joliffe DS. Nephrotoxicity of pentavalent antimonials. Lancet. 1985;1:584.
Veiga JPR, Wolff ER, Sampaio RN et al. Renal tubular dysfunction in patients with mucocutaneous leishmaniasis treated with pentavalent antimonials. Lancet. 1983;2:569.
