Clinico–epidemiological profile of patients of Hansen’s disease in a tertiary care centre in West Bengal

EPIDEMIOLOGY OF HANSEN’S DISEASE IN WEST BENGAL

Authors

  • Md Samim Reza Department of Dermatology, Venereology and Leprosy; Burdwan Medical College and Hospital, Purba Bardhaman – 713104
  • Ashim Kumar Mondal Department of Dermatology, Venereology and Leprosy; Burdwan Medical College and Hospital, Purba Bardhaman – 713104
  • Kaushik Shome Department of Dermatology, Venereology and Leprosy; Burdwan Medical College and Hospital, Purba Bardhaman – 713104
  • Rajarajan Thangaraj Burdwan Medical College and Hospital

DOI:

https://doi.org/10.66344/jpad.v33i3.2293

Keywords:

Hansen's Infection, Borderline Tuberculoid, Reactions, Deformities

Abstract

Objective To determine clinical patterns of Leprosy, to evaluate post disease complications, to establish clinico-bacteriological correlation, to analyse the demographic profile of the study group and to determine the changing trend in pattern in the disease if any.

 

Methods  Ours was a cross sectional study and patients between 15 to 60 years of age, attending Dermatology, Venerology and Leprosy clinic, diagnosed with leprosy between April 2018 to March 2019, were included in study by convenient sampling and their demographic profile, history, general and dermatological examination were recorded and slit skin smear, biopsies were performed before arriving at final diagnosis.

 

Results Borderline tuberculoid (BT) was found to be the most common clinical type (57%), multibacillary leprosy was more prevalent than paucibacillary leprosy with ratio of 3:2, and type 1 reaction was more common in Borderline Tuberculoid and type 2 reactions in Lepromatous Leprosy. 76% patients had nerve involvement at the time of presentation, and 47% had visible deformities.

 

Conclusion In conclusion, when slit skin smear is not decisive and facilities for PCR are not accessible, a constellation of clinical and histological symptoms revealed to be crucial in the diagnosis of leprosy.

References

1. NLEP annual report (2015-2016).

2. Jayanta Kumar Barua, Deep Anurag, Goutam Barik et al.. A Clinico-Epidemiological Study of Leprosy in an Urban Leprosy Centre of West Bengal. IOSR J Dent Med Sci. 2015;15:12-15.

3. Suri SK, Iyer RR, Patel DU, Bandil S, Baxi S. Histopathology and Clinicohistopathological correlation in Hansen’s disease. J Res Med Den Sci. 2014;2(1):37-44.

4. Thakkar S, Patel SV. Clinical profile of leprosy patients: A prospective study. Indian J Dermatol. 2014;59:158.

5. Rita Vipul Vora et al.. Clinicohistopathological correlation in leprosy: A study at a rural based tertiary care centre, Gujarat. Indian J Clin Exp Dermatol. 2016;2(1):23-6.

6. Singh AL, Vagha S J, Agarwal A, Joharapurkar S R, Singh BR. Current scenario of leprosy at tertiary care level hospital of rural central India. Indian J Dermatol Venereol Leprol. 2009;75:520-2.

7. Sarkar J, Dasgupta A, Dutta D. Disability among new leprosy patients, an issue of concern: An institution-based study in an endemic district for leprosy in the state of West Bengal, India. Indian J Dermatol Venereol Leprol. 2012;78:328-34.

8. Pescarini JM, Strina A, Nery JS, et al.. Socioeconomic risk markers of leprosy in high-burden countries: A systematic review and meta-analysis. PLoS Negl Trop Dis. 2018;12(7):e0006622.

9. Patil PR. Determinants of Leprosy with Special Focus on Children: A Socio-Epidemiologic Perspective. Am J Dermatol Venereol. 2013;2(2):5-9.

10. Ojha KS, Chawdhary RC, Choudhary SK. Socio-environmental factors in relation to leprosy at Jaipur. Indian J Lepr. 2015; 56(4):884-8.

11. Reddy BN, Bansal RD. An epidemiological study of leprosy among children in a rural area. Indian J Pediatr. 1983;50(406):497-501.

12. Kar PK, Arora PN. Clinicopathological study of macular lesions in leprosy. Indian J Lepr. 1994;66:435-41.

13. Mondal Avijit, Piyush Kumar, Das Nilay Ket al.. A clinicodemographic study of lepra reaction in patients attending dermatology department of a tertiary care hospital in Eastern India. J Pak Assoc Dermatol. 2015;25(4):252-8.

14. Van Brakel WH, Khawas IB, Lucas SB. Reaction in leprosy: an epidemiological study of 386 patients in west Nepal. Lepr Rev. 1994;65(3):190-203.

15. Donaghy, M. (2003). Practical neurology. 3rd ed. Oxford, UK: Blackwell Publishing Ltd, pp.40-45.

16. Sehgal VN, Sharma PK. Patterns of deformities/disabilities in urban leprosy. Indian J Lepr. 1985;57:183-97.

17. Shumet T, Demissie M, Bekele Y. Prevalence of Disability and Associated Factors among Registered Leprosy Patients in All Africa Tb and Leprosy Rehabilitation and Training Centre (ALERT), Addis Ababa, Ethiopia. Ethiop J Health Sci. 2015;25(4):313–320.

18. Nayak A K, Satheesh R, Shashidhar K. Spectrum of physical deformities in leprosy patients visiting a tertiary care center in Mangalore. Ann Trop Med Public Health. 2017;10:22-6.

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Published

07.08.2023

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Original Articles

How to Cite

1.
Clinico–epidemiological profile of patients of Hansen’s disease in a tertiary care centre in West Bengal: EPIDEMIOLOGY OF HANSEN’S DISEASE IN WEST BENGAL. J Pak Assoc Dermatol [Internet]. 2023 Aug. 7 [cited 2026 Aug. 24];33(3):980-5. Available from: https://www.jpad.com.pk/index.php/jpad/article/view/2293