Papulonecrotic tuberculid with new lesion at the site of tuberculin test: An unusual manifestation

Authors

  • Erwin Abadi Tanesia Department Dermatology Venereology Faculty of Medicine, Sam Ratulangi University, Manado
  • Sebastian Hendry Wibowo Department of Dermatology and Venereology, Prof. Dr. R. D. Kandou Central General Hospital/ Faculty of Medicine Sam Ratulangi University, Manado, Indonesia.
  • Grace Kapantow Department of Dermatology and Venereology, Prof. Dr. R. D. Kandou Central General Hospital/ Faculty of Medicine Sam Ratulangi University, Manado, Indonesia.
  • Ferra Mawu Department of Dermatology and Venereology, Prof. Dr. R. D. Kandou Central General Hospital/ Faculty of Medicine Sam Ratulangi University, Manado, Indonesia.
  • Meilany Durry Department of Anatomic Pathology, Prof. Dr. R. D. Kandou Central General Hospital/ Faculty of Medicine Sam Ratulangi University, Manado, Indonesia.

Abstract

Papulonecrotic tuberculid (PNT) is a form of cutaneous tuberculosis caused by hypersensitivity reaction towards M. tuberculosis. It presents in the form of erythematous papules that can progress into pustules or necrosis before turning into ulcus that heals after several weeks. Tuberculin test is one of the methods for PNT diagnosis. In rare occasions, a PNT lesion can manifest in the location of tuberculin test. A 42-year-old woman present with inflamed dots on both upper and lower extremities for 3 months before. Pruritus, pain, fever, cough, weight loss, night sweat, and myalgia are denied. Two years ago, the patient has a history of taking care of a family with lung tuberculosis. Tuberculin test was done on the patient, and it developed into a new lesion, an unusual occasion. Clinicopathology results of the patient concludes the diagnosis for PNT, for which the patient was given a regiment of antituberculosis drug for 6 months. Two months after the therapy no new lesions were formed, followed by resolution of the lesions in extremities. A follow up check did not find any recurrence of the disease. This case shows a good response towards tuberculosis drug for a case of PNT within months of starting the regiment.  

References

References

Yates V, Walker S. Tuberculosis of the skin. In: Griffiths C, Barker J, Bleiker T, Chalmers R, Creamer D, editors. Rook’s textbook of dermatology. 9th ed. Hoboken: Wiley-Blackwell; 2016. p. 27.5-27.32.

Bolognia J, Jorizzo J, Rapini R. Cutaneous tuberculosis. In: Bolognia J, Jorizo J, Rapini R, editors. Dermatology. 2nd ed. London: Mosby; 2014. p. 1303–9.

Sethi A. Tuberculosis and Infections with Atypical Mycobacteria. In: Kang S, Amagai M, Bruckner A, Enk A, Margolis D, McMichael A, et al., editors. Fitzpatrick’s dermatology in general medicine. 9th ed. New York: McGraw-Hill; 2019. p. 2858–75.

Meghana V, Saravanan G, Karthikeyan K. Papulonecrotic tuberculid. Am J Trop Med Hvg. 2017;97(4):987–8.

Dongre A, Sanghavi S, Khopkar U. Papulonecrotic tuberculid at the site of tuberculin test in a patient with concomitant erythema induratum and papulonecrotic tuberculid. Indian J Dermatol Venereol Leprol. 2013;79(2):248–51.

Tirumalae R, Yeliur I, Antony M, George G, Kenneth J. Papulonecrotic tuberculid-clinicopathologic and moleculer features of 12 Indian patients. Dermatol Pr Concept. 2014;4(2):17–22.

James WD, Elston D, Rosenbach MA, Neuhaus IM, Treat JR. Tuberculids. In : Andrews’ diseases of the skin: Clinical dermatology. 13th ed. Elsevier; 2020. H.329-330.

Chhabra G, Verma P, Sharma S. Koebner phenomenon induced by Mantoux testing in a case of papulonecrotic tuberculid. Trop Doc. 2020;50(1):74–7.

Muto J, Kuroda K, Tajima S. Papulotuberculides post-BCG vaccination. Clin Exp Dermatol. 2006;31:611–2.

Sharma S, Sehgal V, Bhattacharya SN, Mahajan G, Gupta R. Clinicopathologic Spectrum of Cutaneous Tuberculosis: A Retrospective Analysis of 165 Indians. Am J Dermatopathol. 2015;37(6):h.444-50.

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Published

2023-07-02

How to Cite

1.
Tanesia EA, Sebastian Hendry Wibowo, Grace Kapantow, Ferra Mawu, Meilany Durry. Papulonecrotic tuberculid with new lesion at the site of tuberculin test: An unusual manifestation. J Pak Assoc Dermatol [Internet]. 2023Jul.2 [cited 2026Mar.3];33(2):680-3. Available from: https://www.jpad.com.pk/index.php/jpad/article/view/2076

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Case Reports