A rare case of mandibular osteosarcoma with myxoid pattern

Abstract

Osteosarcomas are defined as primary malignant tumors of the long bones with varied histological patterns. Conventional osteosarcoma can be subdivided into osteoblastic, chondroblastic, and fibroblastic histologic variants depending on the extracellular matrix produced by the tumor cells. Other evident histologic variants are the telangiectatic type, small cell, giant cell rich, large cell type, fibrous histiocytoma- type, and epithelioid osteosarcoma.  We present a case of Osteosarcoma with prominent areas of myxoid degeneration, although myxoid areas have been documented in chondrosarcoma and chondroblastic osteosarcoma but the present case is unique because it was devoid of any chondroid tissue formation and it showed a prominent myxoid stroma. An exhaustive literature review could only reveal a single case of jaw osteosarcoma with a prominent myxoid stroma.