Effect of soy isoflavones on acne vulgaris

Authors

  • Puguh Riyanto
  • Prasetyowati Subchan

Keywords:

Acne vulgaris, soy isoflavones

Abstract

Objective To demonstrate the effect of soy isoflavones on acne vulgaris (AV) lesions in female patients.Methods In this randomized pretest-posttest control group design, 25 patients were randomized into 5 groups: isoflavones 40 mg, 80 mg, 120 mg, 160 mg and placebo, and treated for 4 weeks.Results The mean total AV lesions before treatment among the five groups was similar (p=0.259), whereas after treatment significant difference was observed (p=0.001). Intergroup comparison revealed that decrease in the mean total AV lesion count before and after treatment was significant in isoflavone 160 mg group (p<0.05 ), while in the placebo, 40 mg, 80 mg, 120 mg groups it was insignificant (p>0.05 ).Conclusion Soy isoflavones supplementation 160 mg/day can lower total AV lesion.

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Published

2016-11-22

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Original Articles