Normolipemic papular xanthoma with xanthelasma

Authors

  • Aman Dua
  • Alka Dogra
  • Neena Sood
  • Saloni Sachdeva
  • Atul Singla

DOI:

https://doi.org/10.66344/jpad.16.2.2006.860

Keywords:

Xanthelasma, papular xanthoma, normolipemic

Abstract

Xanthomas are a common presentation of disorders of lipid metabolism usually associated with abnormalities of cholesterol metabolism.  A 35 year old female presented to us with the lesions of xanthelasma on the upper eyelids and papular xanthomas on the rest of the body. Routine investigations and systemic examination was normal. Lipid profile was within normal range and serum protein electrophoresis showed normal pattern. Histopathology from a papular lesion showed foamy histiocytes with touton’s type of giant cells. We present a case of normolipemic papular xanthoma with xanthelasma which is a very rare occurrence. 

References

Caputo R, Monti M, Berti E, Gasparini G. Normolipemic eruptive cutaneous xanthomatosis. Arch Dermatol 1986; 122: 1294-7.

Seymour C.A. Xanthomas and abnormalities of lipid metabolism and storage. In: Champion RH, Burton JL, Burns DA, Breathnach SM, eds. Textbook of Dermatology, 7th edn. Oxford: Blackwell Science; 2004. p. 57.65 -57.67

Breier F, Zegler B, Reiter H et al. Papular xanthoma; a clincopathological study of 10 cases. J Cutan Pathol 2002; 29: 200-6.

Horenstein MG. Xanthomas .www.emedicine.com/derm.

Bundino S, Zina AM, Aloi F Papular Xanthoma. Clinical, Histological and ultrastructural study. Dermatologica 1988; 177: 382-5.

Rudolph RL. Diffuse "essential" normolipemic xanthomatosis. Int J Dermatol 1975; 14: 651-6.

Hu CH, Winkelmann RK. Unusual normolipidemic cutaneous xanthomatosis: a comparison of two cases illustrating the differential diagnosis. Acta Derm Venereol 1977; 57: 421-9.

Vail JT Jr, Adler KR, Rothenberg J. Cutaneous xanthomas associated with chronic myelomonocytic leukemia. Arch Dermatol 1985; 121: 1318-20.

Darwin BS, Herzberg AJ, Murray JC, Oslen EA. Generalized papular xanthomatosis in mycosis fungoides. J Am Acad Dermatol 1992; 26: 828-32.

Goerdt S, Kretzschmar L, Bonsmann G. Normolipemic papular xanthomatosis in erythrodermic atopic dermatitis. J Am Acad Dermatol 1995; 32: 326-33.

Caputo R, Passoni E, Cavicchini S. Papular xanthoma associated with angiokeratoma of Fordyce: considerations on the nosography of this rare non-Langerhan’s cell histiocytoxanthomatosis. Dermatology 2003; 206: 165-8.

Downloads

Published

2017-01-03

How to Cite

1.
Dua A, Dogra A, Sood N, Sachdeva S, Singla A. Normolipemic papular xanthoma with xanthelasma. J Pak Assoc Dermatol [Internet]. 2017Jan.3 [cited 2026May1];16(2):116-9. Available from: https://www.jpad.com.pk/index.php/jpad/article/view/860

Issue

Vol. 16 No. 2 (2006): April - June

Section

Case Reports

License

Submission declaration

Authors retain the copyright to their work and grant the 'Journal of Pakistan Association of Dermatologists (JPAD)' the right of first publication under a Creative Commons Attribution 4.0 International (CC BY 4.0) license. This license allows others to share, adapt, and reuse the work for any purpose, including commercial use, as long as appropriate credit is given to the original authors and the journal.

By submitting a manuscript, authors confirm that the work has not been published previously (except as an abstract, lecture, or academic thesis), is not under review elsewhere, and has been approved by all authors and relevant authorities. Once accepted, the article will be openly accessible under the CC BY 4.0 license, ensuring wide dissemination and reuse with proper attribution.