Epidemiologic evaluation of patients with blistering lesions in Sari: A retrospective study
DOI:
https://doi.org/10.66344/jpad.v27i3.46Keywords:
Skin bullous disease, Pemphigus Vulgaris, BullousPemphigoid, Pemphigus foliaceusAbstract
Objective To evaluate the histopathological and demographical features of patients with blistering lesions from the medical records in the pathology unit of Buali hospital in Sari.
Methods This descriptive retrospective study included medical records of 87 patients with bullous lesions during years 2003-2013 which were archived in the pathology unit of the hospital, were reviewed and evaluated. Biopsies were taken by dermatologist after sterilizing of the bullous lesion with betadine and applying local anesthesia with lidocaine 1%. After appropriate tissue slicing, fixation and hematoxylin and eosin staining, slides were examined under microscope by two pathologists. Histopathological and demographic data (such as age, sex, area of involvement, diagnosis) were recorded. The gathered information was analyzed by SPSS16 in terms of central and peripheral statistic distribution.
Results Of 87 patients with bullous lesions, the most common diagnosis was pemphigus vulgaris with 36 (41.4%) patients, followed by bullous pemphigoid with 22 (25.3%) patients, dermatitis herpetiformis with 8 (9.2%) patients, pemphigus foliaceus with 6 (6.9%) patients, epidermolysis bullosa with 4 (4.6%) patients, pemphigus erythematosus with 3 (3.4%) patients and subcorneal pustular dermatosis with 1 (1.1%) patient and 7 cases had uncertain diagnoses. The ratio of female to male was 1.17:1.
Conclusion Our study demonstrated that the frequency of diagnosis of skin bullous lesions in city of Sari is almost similar to other related studies and the most common diagnoses are pemphigus vulgaris, bullous pemphigoid, dermatitis herpetiformis and pemphigus foliaceus.
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Copyright (c) 2018 Masoud Gholpour, Ghasem Rahmatpour Rokni, Mohmmad Rahmani, Bahareh Gholpour, Ali Morad Heidari gorji
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