Widespread verruca vulgaris on plaque psoriasis lesions: An uncommon clinical presentation

Authors

  • Rusdin Isnain Makbul Department of Dermatology and Venereology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia Array (unauthenticated)
  • Nurul Rezki Fitriani Azis Department of Dermatology and Venereology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia Array (unauthenticated)
  • Suci Budhiani Department of Dermatology and Venereology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia Array (unauthenticated)
  • Nurelly Waspodo Department of Dermatology and Venereology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia Array (unauthenticated)
  • Faridha Ilyas Department of Dermatology and Venereology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia Array (unauthenticated)
  • Farida Tabri Department of Dermatology and Venereology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia Array (unauthenticated)
  • Sri Rimayani Malik Department of Dermatology and Venereology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia. Array (unauthenticated)
  • Andi Hardianty Department of Dermatology and Venereology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia Array (unauthenticated)
  • Khairuddin Djawad Department of Dermatology and Venereology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia Array (unauthenticated)

DOI:

https://doi.org/10.66344/jpad.33.2.2023.2181

Keywords:

Psoriasis vulgaris, verruca vulgaris, methotrexate, overlapping

Abstract

Psoriasis is a common, chronic, recurrent, immune-mediated disease that leads to dysregulation of epidermal proliferation. Plaque psoriasis is the most common psoriasis variant characterized with pruritic, well-defined erythematous plaques accompanied with thick silvery scales. Widespread lesions may require long-term immunosuppressive treatments that can lead to certain opportunistic infections such as verruca vulgaris. The role human papillomavirus (HPV) in psoriatic skin lesions is still unclear. It is thought that HPV is associated with the precipitation of psoriatic lesions. We report a case of a 65-year-old male patient with severe plaque psoriasis with an uncommon clinical presentation of widespread verruca vulgaris overlapping the psoriasis lesions thought to be caused by long-term treatment of methotrexate, prompting physicians to be more aware of the potential complications of using immunosuppressants for the management of various immunological diseases.

References

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Published

02.07.2023

Issue

Vol. 33 No. 2 (2023): April-June

Section

Case Reports

License

Copyright (c) 2023 Rusdin Isnain Makbul, Nurul Rezki Fitriani Azis, Suci Budhiani, Nurelly Waspodo, Faridha Ilyas, Farida Tabri, Sri Rimayani Malik, Andi Hardianty, Khairuddin Djawad

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How to Cite

1.
Widespread verruca vulgaris on plaque psoriasis lesions: An uncommon clinical presentation. J Pak Assoc Dermatol [Internet]. 2023 Jul. 2 [cited 2026 Jul. 21];33(2):787-90. Available from: https://www.jpad.com.pk/index.php/jpad/article/view/2181