A Clinico-epidemiological study of painful skin tumors in the West of Iran over eight years (2012-20)
DOI:
https://doi.org/10.66344/jpad.v32i2.1891Abstract
Background Painful Skin Tumors (PSTs) are uncommon. They induce pain with variable severity and their definitive diagnosis requires para-clinical assessment. This study was done to explore some clinico-epidemiological characteristics of PSTs.
Methods This descriptive analytic study was done on patients clinically suspected of PSTs, which was confirmed by para-clinical assessment. Demographic data of the patients and clinical characteristics of PSTs were recorded. Data analysis was done by appropriate statistical tests.
Results A total of 95 patients (54 females and 41 males), with mean age of 33.88±10.56 years, disease history of 15.26±11.33 months, and tumor size of 4.37±3.75 mm were recruited in this study. Our study showed angiolipoma (31.6%) as the most common PSTs. PSTs were also more common as a solitary lesion (91.6%), without familial history (93.7%) in upper limbs (46.3%) with moderate and severe pain (80%). There was a significant relationship between multiple tumors and severity of the pain, location of the tumor, type of lesion, and positive family history (p <0.05).
Conclusion Although our study showed the majority of neuroma and glomus tumors had severe pain, there was no statistically significant relationship between them. However, familial, multiple, and generalized dermatofibroma had significantly mild pain.
References
1. Bhat MR, George AA, Jayaraman J. Painful tumors of the skin - from ENGLAND to LEND AN EGG to BLEND TAN EGG. Indian J Dermatol Venereol Leprol. 2019;85(2):231-4.
2. Millán-Cayetano JF, Segura-Palacios JM, de-Troya-Martín M. Painful skin nodules. Actas Dermosifiliogr. 2015;106(5):423-4.
3. Naversen DN, Trask DM, Watson FH, Burket JM. Painful tumors of the skin. J Am Acad Dermatol. 1993;28(2 Pt 2):298-300.
4. Vieregge EL, Kyei A.Multiple painful skin-colored papules. JAMA Dermatol. 2013;149(2):223.
5. Kavoussi H, Ebrahimi A, Rezaei M. Treatment and cosmetic outcome of superpulsed CO2 laser for basal cell carcinoma. Acta Dermatovenerol Alp Pannonica Adriat. 2013;22:57-61.
6. Feng W, Zhao-Hui T. Cutaneous metastasis as the first symptom: An uncommon presentation of squamous cell lung cancer. Chin M J. 2017;130(1):115-6.
7. Stein RH, Spencer JM. Painful cutaneous metastases from esophageal carcinoma. Cutis. 2002;70(4):230-2.
8. Herzberg AJ, Murphy GF. Painful tumors of the skin. J Dermatol Surg Oncol. 1993;19:250-8.
9. Ozdemir O, Coskunol E, Ozalp T, Ozaksar K. Glomus tumors of the finger: A report on 60 cases. Acta Orthop Traumatol Turc. 2003;37:244-8.
10. Jawalkar H, Maryada VR, Brahmajoshyula V, Kotha GK: Subungual glomus tumors of the hand: Treated by transungual excision. Indian J Orthop. 2015;49:403-7.
11. Okada E, Tamura A, Ishikawa O, Miyachi Y. Tufted angioma (angioblastoma): Case report and review of 41 cases in the Japanese literature. Clin Exp Dermatol. 2000;25:627-30.
12. Lee WJ, Jung JM, Won CH, Chang SE, Choi JH, Moon KC, et al. Clinical and histological patterns of dermatofibroma without gross skin surface change: A comparative study with conventional dermatofibroma. Indian J Dermatol Venereol Leprol. 2015;81(3):263-9.
13. Kang J, Yang P, Zang Q, He X. Traumatic neuroma of the superficial peroneal nerve in a patient: a case report and review of the literature. World J Surg Oncol. 2016;14:242.
14. Penna A, Konstantatos AH, Cranwell W, Paul E, Bruscino-Raiola FR. Incidence and associations of painful neuroma in a contemporary cohort of lower-limb amputees. ANZ J Surg. 2018;88(5):491-6.
15. Fujioka K. Painful cutaneous and subcutaneous tumors accompanied with vascularized appearance using high-resolution ultrasound in dermatology: The acronym “ENGLAND” or “LEND AN EGG”. Biomed J Sci Tech Res. 2019;12(4):9449-53.
16. Pinto-Almeida T, Caetano M, Alves R, Selores M. Congenital multiple clustered dermatofibroma and multiple eruptive dermatofibromas – unusual presentations of a common entity. An Bras Dermatol. 2013;88:63-6.
17. Yazici AC, Baz K, Ikizoglu G, Koca A, Kokturk A, Apa DD. Familial eruptive dermatofibromas in atopic dermatitis. J Eur Acad Dermatol Venereol 2006;20(1):90-92.
18. Park HR, Im SB, Kim HK, Shin DS, Park YL. Painful eccrine spiradenoma containing nerve fibers: A case report. Dermatology. 2012;224:301-6.
19. Singh K, Pai RR, Kini H, Kini UA. Cutaneous angiomyolipoma. Indian J Pathol Microbiol. 2009;52:242-3.
20. Ammanagi AS, Dombale VD, Shindholimath VV. Cutaneous angiomyolipoma. Indian Dermatol Online J. 2012;3(1):40-1.
21. Malik K, Patel P, Chen J, Khachemoune A. Leiomyoma cutis: A focused review on presentation, management, and association with malignancy. Am J Clin Dermatol. 2015;16:35-46.
Downloads
Published
Issue
Section
License
Copyright (c) 2022 Hossein Kavoussi, Deniz Ketabchi, Nader Salary, Fariba Najafi, Elias Salimi
This work is licensed under a Creative Commons Attribution 4.0 International License.
Submission declaration
Authors retain the copyright to their work and grant the 'Journal of Pakistan Association of Dermatologists (JPAD)' the right of first publication under a Creative Commons Attribution 4.0 International (CC BY 4.0) license. This license allows others to share, adapt, and reuse the work for any purpose, including commercial use, as long as appropriate credit is given to the original authors and the journal.
By submitting a manuscript, authors confirm that the work has not been published previously (except as an abstract, lecture, or academic thesis), is not under review elsewhere, and has been approved by all authors and relevant authorities. Once accepted, the article will be openly accessible under the CC BY 4.0 license, ensuring wide dissemination and reuse with proper attribution.
