Clinical efficacy of chloroquine diphosphate in the treatment of discoid lupus erythematosus
DOI:
https://doi.org/10.66344/jpad.v32i1.1834Abstract
Discoid lupus erythematosus (DLE) is the most common clinical type of chronic cutaneous Lupus erythematosus (СLE). In the absence of a timely diagnosis and treatment, it may cause scarring and skin atrophy. The aim of the treatment is a fast and efficient reduction of the inflammatory process. We present a case of a DLE patient who was successfully treated with chloroquine diphosphate (CD). A 25-year-old woman presented with ruby-red plaques over the face, forehead, nose, cheeks, chin that merged into a butterfly-shaped rash around the nose and zygomatic arches. Treatment with СD (250 mg twice a day for two months) resulted rapidly effective with persistent efficacy and led to the almost complete clearance of cutaneous lesions. However, the treatment was discontinued due to visual disturbances.
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