Frequency of positive thyroid peroxidase antibody levels in patients of generalized vitiligo

Abstract

Objective To determine the frequency of positive thyroid peroxidase antibodies in patients of generalized vitiligo.  Methods This cross sectional study was conducted in the Dermatology Unit 1 of Jinnah Hospital, Lahore for a period of six months. 125 cases of generalized vitiligo, of both genders, ages between 15-60 years, and with any duration of disease were enrolled.  Results A total of 125 cases of generalized vitiligo were enrolled. 61.6% (n=77) patients were between 15-30 years of age whereas 38.4 % (n=48) were between 31-60 years of age, Mean was calculated as 31.56±7.77 years, 56.8% (n=71) were male and 43.2% (n=54) were females. Frequency of positive thyroid peroxidase antibodies in patients of generalized vitiligo was recorded in 32.8% (n=41).  Conclusion The frequency of positive thyroid peroxidase antibodies is significant in patients of generalized vitiligo.