A clinical and histopathological study of nevus sebaceous
DOI:
https://doi.org/10.66344/jpad.24.1.2014.170Keywords:
Nevus sebaceous, histopathological, sebaceous glands, tumoursAbstract
Objective To study the clinical and histopathological features of nevus sebaceous (NS). Methods We selected 20 cases of nevus sebaceous for clinical and histopathological evaluation. Results Regarding the clinical appearance of lesions verrucous plaques were seen in 60% patients, papules in 25% and patches in 15%. All of the lesions showed abortive/immature hair follicles characterized by cords of undifferentiated, basaloid cells resembling the embryonic stages of hair follicle. ConclusionNS is a hamartoma consisting of various elements indigenous to the organ and not merely the sebaceous units.ÂReferences
Lantis S, Leyden J, Heaton C. Nevus sebaceous of Jadassohn. Arch Dermatol. 1968;98:117-23.
Morioka S. The natural history of Nevus Sebaceous. J Cutan Pathol. 1985;12:200-13.
Alsaad KO. Skin adnexal neoplasms-Part I: An approach to tumors of pilosebaceous unit. J Clin Pathol. 2007;60:129-44.
Kaddu S. Malignant neoplasms associated with nevus sebaceous. Am J Dermatopathol. 1998;20:615-23.
Cribier B, Scrivener YG. Tumors arising in nevus sebaceous: A study of 596 cases. J Am Acad Dermatol. 2000;42:263-8.
Maheshwari V, Alam K, Prasad S et al. Cerebriform nevus sebaceous: A rare entity. Dermatol Online J. 2006;12:21.
Verma KK, Ovung EM. Epidermal and sebaceous nevi treated with carbon dioxide laser. Indian J Dermatol. 2002;68:23-4.
Mehregan AH. Sebaceous tumors of the skin. J Cutan Pathol. 1985;12:196-9.
Rulon DB, Helwig EB. Cutaneous sebaceous neoplasms. Cancer. 1974;33:82-102.
Weng CJ, Tsai YC, Chen TJ. Jadassohn's nevus of the head and face. Ann Plast Surg. 1990;25:100-2.
Jonathan SD. Epidermal nevus. Dermatol Online J. 2001;7:14.
Ng WK. Nevus sebaceous and apocrine differentiation. Am J Dermatopathol. 1996;18:420-3.
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