Association of melasma with iron deficiency anemia and thyroid disease in females at a tertiary care hospital of Pakistan
Keywords:
Melasma, anemia, thyroid function testAbstract
Objective To determine the association of melasma with iron deficiency anemia and thyroid diseases in females of a tertiary care hospital of Pakistan. Patients and Methods In this retrospective study, the data of 100 adult females with melasma was retrieved from medical records by using the medix system software of the Hospital. Patients’ serum TSH, T3, T4, ferritin and complete blood count was collected. Results The mean age of presentation was 30 years. 31% of melasma patients were found to have anemia with mean Hb level 11.5g/dl. Mean serum ferritin level was 64.9 ng/ ml. Mean serum T4 and TSH were in normal range in all the patients. Conclusion There is no association of melasma with iron deficiency anemia and thyroid diseases in females of a tertiary care hospital of Pakistan.References
Miot LD, Miot HA, Silva MG, Marques ME. Physiopathology of melasma. An Bras Dermatol. 2009; 84:623-635.
Moin A, Jabery Z, Fallah N. Prevalence and awareness of melasma during pregnancy. Int J Dermatol. 2006; 45: 285-288.
Lutfi RJ, Fridmanis M, Misiunas AL, Pafume O et al. Association of melasma with thyroid autoimmunity and other thyroidal abnormalities and their relationship to the origin of the melasma. J Clin Endocrinol Metab 1985; 61: 28-31.
Kauh YC, Zachian TF. Melasma. Adv Exp Med Biol 1999; 455: 491.
King RA, Oetting WS. Disorders of melanocytes. In: Freedberg IM, Eisen AZ, Wolff K et al editors. Fitzpatrick’s dermatology in general medicine. New York: McGrawHill 1999: 996-1000.
Richelle M, Sabatier M, Steiling H, Williamson G. Skin bioavailability of dietary vitamin E, carotenoids, polyphenols, vitamin C, zinc and selenium. Br J Nutr. 2006; 96: 227-38.
Perez M, Sanchez JL, Aguilo F. Endocrinologic profile of patients with idiopathic melasma. J Invest Dermatol 1983; 81: 543-45.
Najad SB, Khodaiiani E, Herizchi H, Mehrabi P. Frequency of iron deficiency anemia, folate and vitamin B12 deficiency in patients with melasma. Med J Tabriz Univ Med sciences 2012; 34(2): 8-12.
Qazi I, Dogra NK, Dogra D. Serum iron profile in female patients of melasma. Asian Pac. J. Health Sci. 2017; 4(2): 141-46.
Behrangi E, Baniasadi F, Esmaeeli S, Hedayat K, Goodarzi A et al. Serum iron level, ferritin and total iron binding capacity level among non-pregnant women with and without melasma. J Res Med Sci. 2015; 20(3): 281-83.
Gopichandani K, Arora P, Garga U, Bhardway M, Sharma N and Gautam RK.. Hormonal profile of melasma in Indian females. Pigment Int 2015; 2: 85-90.
Kiani A, Ahmari M, Rezvanfar MR. Association of melasma with thyroid disorders. Iran J Dermatol 2006; 9:154-58.