Non Dermatophyte Onychomycosis Caused by Aspergillus in a Patient with Systemic Lupus Erythematosus: a Case Report

Authors

  • Devi Dwi Sintia Department of Dermatology and Venereology, Dr. Soetomo General Hospital, Surabaya, Indonesia
  • Menul Ayu Umborowati Department of Dermatology and Venereology, Dr. Soetomo General Hospital, Surabaya, Indonesia
  • Sunarso Suyoso Department of Dermatology and Venereology, Dr. Soetomo General Hospital, Surabaya, Indonesia
  • Evy Ervianti Department of Dermatology and Venereology, Dr. Soetomo General Hospital, Surabaya, Indonesia
  • Linda Astari Department of Dermatology and Venereology, Dr. Soetomo General Hospital, Surabaya, Indonesia
  • Hasnikmah Mappamasing Department of Dermatology and Venereology, Dr. Soetomo General Hospital, Surabaya, Indonesia
  • Trisiswati Indranarum Department of Dermatology and Venereology, Dr. Soetomo General Hospital, Surabaya, Indonesia
  • Yuri Widia Dermatology and Venereology Airlangga University a:1:{s:5:"en_US";s:0:"";}

Keywords:

Non dermatophyte onychomycosis, Aspergillus onychomycosis, Systemic Lupus Erythematosus, Itraconazole

Abstract

Onychomycosis is a fungal infection of nails, occasionally found on fingernails. Non-dermatophytes molds (NMDs), such as Aspergillus spp., are increasingly reported, particularly in immunocompromised patients. We report a case of a 19-year-old female with systemic lupus erythematosus (SLE), treated with immunosuppressive drugs, presenting with proximal subungual onychomycosis. Fungal cultures confirmed Aspergillus flavus. The patient achieved complete clinical and mycological cure after three months of pulsed oral itraconazole therapy. This case emphasizes the need for proper mycological diagnosis in immunocompromised patients presenting with nail abnormalities.

Published

2025-09-30

How to Cite

1.
Devi Dwi Sintia, Menul Ayu Umborowati, Sunarso Suyoso, Evy Ervianti, Linda Astari, Hasnikmah Mappamasing, Trisiswati Indranarum, Widia Y. Non Dermatophyte Onychomycosis Caused by Aspergillus in a Patient with Systemic Lupus Erythematosus: a Case Report. J Pak Assoc Dermatol [Internet]. 2025Sep.30 [cited 2025Oct.12];35(3). Available from: http://www.jpad.com.pk/index.php/jpad/article/view/2945

Issue

Vol. 35 No. 3 (2025): July- September

Section

Case Reports

Most read articles by the same author(s)