Pachydermoperiostosis - a case report


  • Rushma Shrestha National Academy of Medical Sciences, Bir Hospital, Kathmandu
  • Niraj Parajuli
  • Anupama Karki


Pachydermoperiostosis, cutis verticis gyrata, hyperhidrosis, clubbing


Pachydermoperiostosis is a rare autosomal dominant condition but autosomal recessive families probably can also occur. At least two gene mutations have been implicated, namely HPGD and SLCO2A1. This condition usually presents at puberty with progressive enlargement of the joints due to pachydermia, periostosis, and clubbing. Disease progresses for 5–20 years before stabilizing. We describe a case of 22 year old male who presented with thickened skin on the face and scalp (resembling cutis verticis gyrata), palmoplantar hyperhidrosis and clubbing.

Author Biographies

Rushma Shrestha, National Academy of Medical Sciences, Bir Hospital, Kathmandu


Niraj Parajuli


Anupama Karki



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How to Cite

Shrestha R, Parajuli N, Karki A. Pachydermoperiostosis - a case report. J Pak Assoc Dermatol [Internet]. 2019Oct.6 [cited 2024Jul.13];29(2):257-9. Available from:



Case Reports