Efficacy and safety of thalidomide in treatment of prurigo nodularis


  • Uzma Ahsan
  • Sumara Rashid
  • Uzair Wazir


Thalidomide, pruritus, prurigo nodularis


Objective To determine the efficacy and safety of thalidomide in treatment of idiopathic prurigo nodularis. Methods A total of 12 patients were enrolled in the study. Patients of child bearing potential and those with active systemic disease were excluded. All the patients had the histopathological confirmation of diagnosis. Patients were given 100mg/day of thalidomide for a period of three months. Follow up visit was every one month and therapy was stopped at three months. Patients were again evaluated for relapse two months after stopping the treatment. Results 7 (58.3%) patients had successful response to the treatment. 3 (25%) patients had a partial response and 2 (16.7%) had unsuccessful treatment.  Conclusion Thalidomide is safe and effective treatment option for idiopathic recalcitrant prurigo nodularis. 


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How to Cite

Ahsan U, Rashid S, Wazir U. Efficacy and safety of thalidomide in treatment of prurigo nodularis. J Pak Assoc Dermatol [Internet]. 2018Dec.13 [cited 2024Jun.24];28(2):193-8. Available from: https://www.jpad.com.pk/index.php/jpad/article/view/1233



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