Relationship of amino acid concentrations in blood with occurrence of dermatophytosis
DOI:
https://doi.org/10.66344/jpad.v28i2.1069Keywords:
Dermatophytes, high performance liquid chromatography, tinea corporisAbstract
Objective To compare the free amino acid concentrations of the blood in subjects suspected to tinea corporis with healthy individual.
Methods Blood samples from 40 adult (18-40 year) patients of mycologically-proven tinea corporis and 44 age- and sex-matched healthy controls were taken and assayed using high performance liquid chromatography for free amino acid levels.
Results 90% of patients showed higher free amino acids levels than controls. Methionine did not show significant difference in concentration between infected and healthy individuals. However, concentrations of glutamine, asparagine, phenylalanine, and tyrosine were significantly high in infected individuals with dermatophytes (p<0.005).
Conclusion Our finding provide information about the possible role of free amino acids in pathogenicity of dermatophytes.
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