Aplasia cutis congenita in two brothers – a rare occurrence
Keywords:
Aplasia cutis congenita, familialAbstract
Aplasia cutis congenita (ACC) is characterized by the absence of a portion of skin in a localized or widespread area at birth. It is a rare disorder with a complicated pattern of inheritance. No unifying theory can account for all lesions of ACC. Apart from the isolated finding of aplasia cutis; several reports have associated it with a large number of developmental anomalies. Therefore, a complete physical examination should be performed to search for associated physical anomalies or recognizable malformation syndromes. We document two brothers aged, 6 years and I year, who presented with aplasia cutis congenita at almost the same location on scalp.References
Blunt K, Quan V, Carr D, Paes BA. Aplasia cutis congenita: a clinical review and associated defects. Neonatal Netw 1992; 11: 17-27.
Chitnis MR, Carachi R, Galea P. Familial aplasia cutis congenita. Eur J Pediatr Surg 1996; 6:100-1.
Karg E, Bereg E, Gaspar L et al. Aplasia cutis congenita after methimazole exposure in utero. Pediatr Dermatol 2004; 21: 491-4.
Visva-Lingam S, Jana A, Murray H, John E. Preterm premature rupture of membranes associated with aplasia cutis congenita and fetus papyraceous. Aust N Z J Obstet Gynaecol 1996; 37: 90-1.
Ribuffo D, Costantini M, Gullo P et al. Aplasia cutis congenita of the scalp, the skull, and the dura. Scand J Plast Reconstr Surg Hand Surg 2003; 37: 176-80.
Benjamin LT, Trowers AB, Schachner LA. Giant aplasia cutis congenita without associated anomalies. Pediatr Dermatol 2004; 21: 150-3.
Verhelle NA, Heymans 0, Deleuze JP et al. Abdominal aplasia cutis congenita: case report and review of the literature. J Pediatr Surg 2004; 39: 237-9.
Davidson AW, Hosalkar HS, Hill RA, Monsen F. Radial dysplasia with localized cutis aplasia congenita. J Pediatr Orthop 2003; 12: 398-401.
Bigliardi PL, Braschler C, Kuhn P et al. Unilateral aplasia cutis congenita on the leg. Peiliatr Dermatol 2004; 21: 454-7.
Arif A, Tajammul A. Aplasia cutis congenita. Pak Ped J 1996; 20: 175-80.
